Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21378 Idelalisib GSE70138 SKL.C Human 24h 0.37uM EID0064
Types Number Response transcription factors
Up-regulation 67 VPS72; NFATC4; FOXF2; GFI1B; TRIB3; PAX6; PIAS1; ETS1; ATOH1; TGFB1; RAD21; ZNF589; TDP2; MYBL2; PAXBP1; NFE2; ZNF536; TAL1; MYCN; HOXD1; TFAP2A; ILF2; ELF4; NKX2-1; FOXM1; IRF1; ARNT2; CUX2; ERF; GATA2; MYBL1; GATA6; PEX14; BRWD1; ZNF721; NCOA2; TOX3; ZNF165; ZNF232; ARID5B; TSC22D2; MAF; ZFP36L2; NR1H4; SOX18; LITAF; SMAD7; HIRA; ZHX2; SOX9; CARHSP1; IRF6; LPIN2; VDR; TEAD4; SHOX2; PAWR; RBPMS; LIN28A; HLF; ATF3; NR2F1; MYRF; NFE2L3; CRYM; ID4; ID1
Down-regulation 51 SSRP1; EYA2; ARID4A; SIX1; TRIP6; JARID2; CREB3L1; ADNP; MLX; NR4A2; TRIM32; ZBTB1; DNAJC2; HOXA5; PRRX1; ETV5; IRF4; ING3; SIX2; ZBTB18; PURA; MEIS1; HOXB6; FOXD1; SOX10; AFF1; ZNF580; HOXB7; MITF; TAF10; STAT6; SMARCA2; NR2F2; MDM2; BTG1; REPIN1; HOXC6; MED1; MAGED1; FOSB; CREB1; WWTR1; KLF10; EGR3; SSX1; FOXC1; KDM5D; PEG3; ASCL1; NFATC3; BASP1