Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21377 Idelalisib GSE70138 SKL.C Human 24h 1.11uM EID0064
Types Number Response transcription factors
Up-regulation 70 TCFL5; MTF2; MNDA; TFCP2; VPS72; IKBKAP; ZNF91; PAX5; BCL11A; CNOT3; SMARCC2; CERS4; ZKSCAN1; TAF4; BAZ1B; SOX11; ZNF133; POU2AF1; ARID1A; ZNF266; HOXB5; SMAD1; LEF1; ZNF12; ID2; L3MBTL1; ZNF112; HOXB6; MAFB; MED13; TULP3; PAXBP1; ZNF107; MED24; HLX; MED1; CBFA2T3; MYCL; IRF8; HOXB2; BCL6; CUX1; AR; TERF2; PCGF2; SALL1; ZNF423; HMG20B; TFEB; SHOX2; CUX2; EMX2; MYT1L; BNC2; EGR3; WWTR1; CDK2; PBX3; CREB3L2; ZBED2; BHLHE41; ST18; TCF4; BASP1; ZBTB20; ID4; KDM5D; MEIS2; WT1; NFATC3
Down-regulation 44 XBP1; TFDP1; SMARCC1; PEX2; RAD21; ELF1; RNF4; SFPQ; EGR4; ZMYM2; TSC22D2; ENY2; FUBP1; CREBZF; LHX6; AHR; UBE2B; ETS1; SP100; TULP4; ZNF165; AGO2; CBFB; CTNNB1; NCOA2; OSR2; HSBP1; TGIF1; ATF3; TOX; HOXC6; TOB1; ETS2; SMARCA2; IRX5; ZNF217; TCEB2; YWHAB; TOX3; USP22; HTATIP2; MAF; ID1; E2F2