Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21367 Bms-509744 GSE70138 SKL.C Human 24h 0.12uM EID0064
Types Number Response transcription factors
Up-regulation 60 NFATC4; FOS; ETS1; PRDM2; TFAP2A; CDIP1; SOX15; ZBED2; SUPT3H; RB1; FOXG1; POU5F1B; PIAS1; MYBL1; DDX17; TOX; TCF7L1; SOX10; PTTG1; TWIST1; TCEA1; MED14; XRCC6; SALL2; NCOA2; FOXE1; ARNT2; MNT; NR2F6; MYBL2; HIRA; PQBP1; TLE4; TRIM22; CARHSP1; FOXM1; PRRX1; BCL11A; SHOX2; MKL2; RBFOX2; RBBP8; CITED1; POU2AF1; ZHX2; TEAD4; HOXD1; HIC2; NANOG; LIN28A; EGR2; JUP; PBX3; IFI16; ZSCAN18; TRPS1; ID4; ID1; PBX1; PEG3
Down-regulation 49 TP53; VEZF1; ZBTB18; TRIB3; HSF2; RUNX3; NKX3-1; ING3; ZNF443; EDF1; MYCN; SCAND1; BMI1; ZBTB1; MED1; PURA; BCLAF1; ZBTB38; PIR; SMAD3; TSC22D2; ETS2; MECOM; NR1D2; SMAD2; HOXB7; SMAD5; PCGF2; BTG1; YWHAB; SOX17; TOX3; CTNNB1; MYT1L; HTATIP2; IRX5; CREB1; KDM5D; CHD7; DACH1; ZKSCAN1; LEF1; NR2F2; HOXB6; MAGED1; HOXC6; NFATC3; RELB; E2F2