Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21356 Osimertinib GSE70138 SKL.C Human 24h 0.04uM EID0064
Types Number Response transcription factors
Up-regulation 26 DAXX; TAF11; BBX; ZIC1; EHMT2; KLF2; ZNF160; ZFHX4; INSM1; ZMYND8; TP63; SERTAD2; MYBL1; RORA; LITAF; CREBL2; FOXD1; HEY1; SHOX2; CREB1; NFIB; ASCL1; BASP1; PEG3; ZNF652; NFATC3
Down-regulation 20 REST; NFATC1; ADNP; TLE4; ZNF266; GATA6; SAP18; NCOA2; NKX3-1; PITX2; SOX17; FOXO1; RUNX3; ZFP36L2; PBX1; TFAP2C; MAFB; CALR; WT1; E2F2