Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21355	Osimertinib	GSE70138	SKL.C	Human	24h	0.12uM	EID0064

Response Information :

Types	Number	Response transcription factors
Up-regulation	50	TAF7; NR3C1; HHEX; BRD2; HIPK1; MAFB; KDM5A; IRF1; ZFP36L2; TOPORS; NCOA2; LPIN2; RBPJ; AEBP1; GTF3A; ESR1; POU4F1; ZNF107; BTG1; ZNF267; SERTAD2; IFI16; IRF7; BACH2; GATA6; NR1D2; POU2AF1; NKX2-1; ASCL1; FOXD1; LMCD1; HTATIP2; ATF4; LYL1; CUX2; BMI1; LITAF; WWTR1; ZMYND8; MECOM; HLF; IRX5; ZBED2; KLF2; BASP1; NR1H2; ID4; YWHAB; NFATC3; ATF3
Down-regulation	42	ERBB2; EMX2; ZNF33B; NFKBIA; CHD8; IRF8; HDAC1; KMT5A; PATZ1; TLE4; PBX1; PLAGL1; EWSR1; ZBTB18; FOSL2; KLF5; ZNF189; ATF5; ZSCAN18; TRIP6; HOXB13; TCF7L1; MITF; NR4A2; APEX1; FOXF1; NR4A1; SPIB; PBX3; DACH1; FOXG1; MAGED1; CENPF; FOSB; HOXB6; TOX; NR2F1; PITX1; CREB1; TRIM29; TBX3; RELB