Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21354	Osimertinib	GSE70138	SKL.C	Human	24h	0.37uM	EID0064

Response Information :

Types	Number	Response transcription factors
Up-regulation	62	SMARCD2; HIPK1; TAL1; NFE2; IKBKAP; ASH2L; VEZF1; TGFB1; ZNF239; ZNF131; DR1; CTBP1; SP110; NR4A2; MAFB; GFI1B; CEBPD; RUNX3; ZNF304; WWC1; SMAD2; RUNX1; ZNF266; RERE; ATF7IP; ZFP36L1; CERS4; ZNF24; HBP1; GLI3; EGR1; PSIP1; ZNF217; ERG; CREBL2; TOB1; INSR; AEBP1; JUP; EHF; MKL2; TAF10; UBE2B; TP63; FOXO1; GTF3A; DACH1; EGR3; ERBB4; ZFPM2; IRF7; MYRF; HMGA1; KDM5D; PIR; ST18; NFATC3; ATF5; WT1; PEG3; SOX9; BHLHE41
Down-regulation	60	THAP11; ABL1; BTG1; CREB3L1; PPRC1; ZFHX3; TRIB3; TXNIP; CCNH; LITAF; POU4F1; PKNOX2; NR2F6; ZNF652; ZNF124; EN1; AES; ZNF721; ZNF12; NFE2L1; RBPJ; ZNF107; C1QBP; ZNF91; BASP1; TBX3; HOXB13; ETS2; RFX5; PBX3; HSBP1; MYBL1; ZNF430; RAN; TRIP6; MLXIP; ID1; TLE4; PBXIP1; SALL1; TCF4; NKX3-1; SNAI2; SPIB; IRX5; MEOX2; IRF6; ID3; SIX1; NR2F2; CREB3L2; ELF5; ASCL1; MED21; KLF2; YWHAB; ZIC1; MAF; NR3C1; SUV39H1