Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21353	Osimertinib	GSE70138	SKL.C	Human	24h	1.11uM	EID0064

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	TFDP2; ZNF33B; TBX2; EN1; ZSCAN31; ZNF426; GABPA; HIPK1; PNRC1; THRA; TCF21; BRD8; HMGB3; SKI; MXD1; TFEC; NR3C1; SOX11; ZNF10; NFKB2; SMARCC2; BACH1; ZBED1; ZNF14; NFE2L1; DLX4; IKZF5; ZNF83; BRWD1; ID4; ZNF423; MECOM; THAP10; KLF11; MYCL; EGR2; ASH2L; PHIP; GATA6; ESRRG; CDX1; MYCN; PRPF6; HOXB7; NRBF2; DPF2; MYB; ZNF140; REPIN1; PAWR; HEY2; NR1H4; UBE2B; ETS2; ILF2; PITX2; HBP1; MNDA; HLX; FOXF1; TXNIP; FOXF2; ZEB1; CIR1; ZNF12; NR4A3; ZBTB20; ZNF160; AHR; KDM5D; INSM1; PBXIP1; PAX6; ID1; CBFA2T3; BATF3; HTATIP2; CDK9; KLF6; OVOL2; MEF2A; MEOX2; IRF9; NEUROD1; KLF10; SMAD7; TLE4; ATF3; TSC22D2; ZEB2; BTG1; SMAD4; NKX2-2; TTF2; SMAD6; TOX3; KLF2; TCEB2; TCF7L2; MEIS1; CENPF; ZFPM2; ZNF302; TFAP2A; ERBB4; PBX3; ZIC1; JUP; TWIST1; DACH1; MXI1; MYRF; HMGN3; MAFB; ID3; NR2F1; BHLHE41; ST18; KLF9; MAF; BASP1
Down-regulation	79	PARP1; HMGA2; FOSL1; TBP; TRIB3; CNOT3; ZNF692; FOXK2; MED25; GLI3; PAX5; BACH2; C1QBP; USP21; JARID2; LOXL2; AR; MAFG; TRIM33; CBX6; FOXG1; ZMYM2; PIAS2; SMAD3; SETD2; PIAS3; ATF5; PATZ1; ZNF593; CTR9; ZBTB25; MAGED1; ZNF580; BRD4; BCL11B; ZNF654; PRKDC; EGR1; EYA2; MKL2; ZNF91; NKX3-1; TRRAP; CEBPD; UBP1; LEF1; HHEX; TCEA1; SLC2A4RG; ZFP36L1; HLF; BCL6; STAT6; CITED1; FOXE1; TP63; TBX3; AES; RYBP; SMAD5; ZHX2; BNC2; SIAH2; SIX1; HOXC10; TBL1X; SUB1; TGFB1I1; BCL3; ADRB2; FOSB; SREBF1; ESR1; TFAP2C; NFATC3; SOX9; RELB; SUV39H1; E2F2