Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21350 Gsk-3-inhibitor-ii GSE70138 SKL.C Human 24h 0.04uM EID0064
Types Number Response transcription factors
Up-regulation 106 TCFL5; ECD; PBX3; ISL1; BRIP1; RFX2; ADRB2; EHMT1; NFATC1; KMT2B; TLE4; TCF20; MED27; MNDA; RBBP4; ORC2; CCNE1; HIVEP2; TAF1A; CHD1; HSF2; PHOX2B; CNOT3; ZNF239; ZNF175; ZEB2; MXD1; HOXD3; JUNB; SMAD6; NFRKB; ZNF248; BTAF1; CAPN15; FLNA; CXXC1; HOXC6; ZNF165; CARHSP1; USP16; PHF1; YBX2; DDIT3; ZNF93; ZNF131; IL16; PAXBP1; NKX2-2; TCF7L2; RRN3; OSR2; KMT2A; SAFB; KDM5A; ZSCAN31; EP400; NFAT5; TTF2; KLF2; MED6; CBFB; TSC22D1; ZNF587; ASXL1; FOXJ1; GATA2; MAFG; LIN28A; NPAT; NKX3-1; KLF4; ANKRD1; SIX3; YAP1; E2F3; DLX2; TAF9B; BRCA2; SOX10; DLX5; ZNF189; SMAD2; MYRF; MAFB; HOXD1; BCLAF1; TFAP2C; NR1D2; GATA6; SNAI2; MITF; ERG; FOSB; ID3; LITAF; SHOX2; ETS2; ID1; TBX3; PEG3; ZNF423; FOXC1; CALR; MAGED1; BASP1; NFATC3
Down-regulation 90 ERBB2; BRF2; IRF1; ZFPM2; TRIB3; BATF3; ZBTB7A; TCF3; TAF6; FOXG1; ITGB3BP; RELA; NFIC; TOX; CUX2; RERE; EYA2; HMGB1; NLK; VEZF1; ZBED2; PRKDC; CNOT2; ATN1; SMARCA5; VGLL4; IRF2; TRIP6; KAT2B; ZNF3; NR2F6; WWTR1; SLC2A4RG; RNF14; MYBL1; RARA; RREB1; NCOR2; TERF1; SERTAD2; STAT5A; NR3C2; TRIM16; PLAG1; SMAD1; BRD4; IRF4; RORA; MED21; HMGB2; AR; ATF5; PAX5; NCOA2; KLF13; ZFP36L1; TCEA1; NEUROD1; SAP30; IRF7; RUNX3; ZBTB18; NAB1; ZKSCAN1; ZIC1; SATB2; PLAGL1; ARNTL2; TWIST1; ZBTB20; NR0B1; EHF; CREB1; INSM1; TXNIP; ZBTB38; ASCL1; NFE2L3; POU2AF1; MXI1; IFI16; MAF; ID4; KDM5D; PBX1; BHLHE41; ATF3; GATA3; E2F2; RELB