Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21343 Motesanib GSE70138 SKL.C Human 24h 0.12uM EID0064
Types Number Response transcription factors
Up-regulation 31 CREB3; NCOA1; SIX2; SIX1; CNOT6; SMARCA2; NFE2; SMARCD3; TRIM22; MEF2A; COPS5; GLI3; TRIP6; HLTF; TSC22D2; RUNX1; SMAD1; TRIM29; SOX11; NCOA2; NR1D2; TCF4; FOXO1; FLNA; CHD7; HMGN3; ERG; ZIC1; EGR2; NFATC3; CREB1
Down-regulation 37 ARNT2; CREG1; GATA6; FOXA2; TRIB3; PHF20; ELF1; FOXF2; BCL6; NR5A2; FOXE1; RBBP7; MXI1; NEUROD1; LMCD1; RORA; CTNNB1; PAX6; IRF6; ETS2; ENO1; KLF4; NR1H2; RBPMS; MYT1L; SATB2; LIN28A; HLF; HES1; TBX3; SIAH2; ID3; YWHAB; NFE2L3; ID1; BASP1; E2F2