Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21325 Gsk-1059615 GSE70138 SKL.C Human 24h 0.12uM EID0064
Types Number Response transcription factors
Up-regulation 59 MTF2; TFDP2; CCNT1; NR4A2; RNF10; NR2C1; GTF2F1; ZMYND8; CERS6; EYA2; TAF10; CREBL2; ZNF160; JUND; ASH2L; SAFB2; ZNF195; HAND1; PHIP; KLF1; ZNF331; SATB2; FOXF2; ZNF264; MAFB; LMCD1; SMAD7; AES; BHLHE41; ZNF721; ELF3; RBPMS; DNMT3B; MITF; HMGA1; JUP; ATF3; HLTF; ZFPM2; PCGF2; LIN28A; ID4; PDLIM1; SSX1; AFF1; ZBTB20; LEF1; CD3D; PITX1; PIR; MECOM; POU2AF1; ELK3; TOX3; PBX1; ESR1; ERG; WT1; MYRF
Down-regulation 34 TRIB3; NRIP1; PAX5; PSPC1; BRIP1; BASP1; NCOA1; CCNE1; RARA; CDK8; POLR3C; ENO1; KLF11; EZH2; FOXN3; TCF7L1; SOX11; ZFP36L1; ZNF165; BTG1; SPIB; FLNA; PQBP1; TBL1X; KLF5; FOXA1; SIAH2; TFAP2C; ELF5; HEY1; NFATC3; ASCL1; HOXC6; CREB1