Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21323 Gsk-1059615 GSE70138 SKL.C Human 24h 1.11uM EID0064
Types Number Response transcription factors
Up-regulation 107 TSC22D3; FOXO4; TCF7; NFATC4; DBP; TCEA2; EZH1; ECD; NRBF2; NONO; AATF; HDAC6; ELF4; LPIN2; BRD8; GFI1; TAF5; ZNF764; ATF7IP; BACH1; ZNF45; ZBTB14; ZNF83; INSR; NFKB2; BRD2; POU2F1; MNT; ZNF212; NAB1; DDX17; CBFA2T2; ZNF264; DDIT3; TFDP2; CBX7; TAF10; HBP1; TRRAP; GATA6; ASXL1; PBX2; NFIL3; TCF25; DNMT3B; FLNA; PHF1; MED12; CEBPD; ZNF32; SMARCC2; ASH2L; HOXC4; MDM4; CARM1; BMI1; ZNF160; JARID2; ING2; THAP1; ZNF587; ZNF24; CARHSP1; PHF20; MED1; SERTAD2; RCOR3; ATF4; RBPJ; SIRT2; ZNF721; NFAT5; PTTG1; TRIM16; TERF1; STAT2; WWTR1; ZBTB16; MXI1; JUP; LITAF; KLF9; CUX1; KLF11; LMCD1; EYA2; NKX3-1; TERF2; PBXIP1; EGR2; NR1D2; MAFB; BCL3; TOB1; ZFP36L2; ZBTB20; ARNTL2; ZEB1; TFAP2A; MAF; TXNIP; ST18; NFATC3; HMG20B; CITED2; KDM5D; ID1
Down-regulation 89 HDAC2; RUVBL1; MEF2C; BHLHE40; PARP1; PGR; GTF2A2; ZNF91; ILF2; MYCBP; TP53; CCNC; IRF4; C1QBP; TCF4; FOXG1; FOXF1; TSC22D2; ZNF146; SMARCB1; JAK2; NLK; EGR3; GFI1B; NOC2L; HHEX; KAT6B; PFDN5; NEDD8; CREB5; EMX2; SUB1; MEIS2; ATF5; SMAD1; WDR77; PAX5; AHR; SOX11; PEG3; BCLAF1; ZNF512B; SIX3; ETS2; CHD9; ZNF467; ZNF43; HEY2; ZNF593; TRIM22; ID2; HOXB5; TRIP6; NR4A1; ZFP36L1; MNAT1; TFEC; KLF1; TRIM29; ZNF430; HOXB6; RAN; CTBP2; MITF; SIAH2; AR; FLI1; ID3; PLAGL1; ESR1; SMARCA2; NR4A2; MEIS1; TWIST1; ZNF165; TBX3; PBX1; SIX1; NANOG; MYT1L; FOSB; ERG; ZSCAN18; DACH1; TOX3; ADRB2; HOXB2; PPARG; LEF1