Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21314 Doramapimod GSE70138 SKL.C Human 24h 0.04uM EID0064
Types Number Response transcription factors
Up-regulation 93 PIAS4; THAP7; NFATC4; EGR2; ZNF623; ZNF7; ZNF532; BACH2; MYBL1; TFAP2A; STAT4; MYBL2; ACTL6A; TTF2; VPS72; SATB1; TCF21; HDAC9; ELF4; SOHLH2; BCL10; TBX21; SAP130; ZNF606; TAL1; EPAS1; IRF6; UBE2L3; PSMC3; ZNF85; TRIB3; FOXF2; TRIM24; HOXD1; ILF2; ERF; ARNT2; FOXK2; BCL11A; HHEX; ZNF267; MED14; CCNE1; SOX18; BRIP1; PEX14; GATA6; SOX10; IRF9; ZNF544; ZFP36L2; ZHX2; CARHSP1; HIC2; TBX1; ZNF557; TERF2; MEOX1; FOXG1; LPIN2; VGLL1; KLF11; DAXX; ID4; NR5A2; HOXB13; ARNTL2; E2F8; NEUROD1; ZBED2; HLX; CUX2; EHF; CDK2; MYRF; CTBP2; NR2F1; ZNF232; SMAD6; PAWR; TP63; SMAD7; ZNF217; WWTR1; NR0B1; MXI1; EGR3; NFE2L3; MEIS2; ID1; ELF5; WT1; NFATC3
Down-regulation 71 XBP1; FOXO3; TULP4; NFKB1; BRD8; URI1; EDF1; ING3; SSRP1; RLF; HIVEP2; NCOA1; FOSB; MSC; TRIP6; NFIL3; NR1D2; CREB3L1; ZNF84; MSX1; BCLAF1; ZBTB38; CREG1; ELF1; BRD2; YWHAB; ZNF226; HOXC6; ZMYND8; BRD4; PURA; CTR9; ZNF160; CEBPG; MTA1; PPARGC1A; RBM39; SSBP2; CREB1; DNAJC1; HMGB2; YBX3; SATB2; TLE4; SREBF1; TCF4; ECD; HLTF; KLF6; ZNF721; ESR1; TRIM32; IRX5; RBPMS; TRIM16; NR1H2; MAGED1; PPARG; ETS2; PITX1; TBX3; KDM5D; BTG1; LEF1; ZIC1; PIR; KLF9; ATF5; CITED2; BASP1; SUV39H1