Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21306 Ast-1306 GSE70138 SKL.C Human 24h 0.37uM EID0064
Types Number Response transcription factors
Up-regulation 60 IKZF1; ZNF672; JUP; ZMYND11; NFIL3; ZFHX4; JUND; CRY1; MECOM; E2F6; PBX2; ERG; MKL2; SSBP2; CEBPD; SMAD1; ID2; SMAD6; ZEB2; PLAGL1; PSPC1; CDK8; TOX; CITED2; GATA2; IRF4; SMAD7; PHIP; RCOR3; EYA2; HMGA1; PPP1R13L; ZIC1; AHR; ATF4; JUNB; PLAG1; PBX3; CHD7; HLTF; LMCD1; TCF7L2; SMARCA1; RUNX3; MNDA; AEBP1; SHOX2; SAP30; PIR; SOX11; DACH1; FOXO1; TRIM29; TWIST1; HTATIP2; ZNF423; ZEB1; ATF5; NFATC3; ELK3
Down-regulation 63 HMGA2; EN2; FOSL1; IRF8; NR2E1; TRIB3; BNC1; MTDH; EGR1; SNAI1; C1QBP; NCOA6; MED23; NR2F2; HOXD10; TRIM22; EGR3; SIAH2; ELF1; SNAI2; BAZ1A; NR1H4; HDAC1; NR4A1; RNF138; SMAD3; OLIG2; ZNF267; HOXD1; EMX2; MAF; DLX2; CTNNB1; SALL1; NHLH2; BCL11A; TBL1X; IFI16; NEUROD1; TLE4; CDK2; HEY1; ZBTB38; ZNF264; LEF1; YWHAB; HIRA; ZNF131; KLF10; BNC2; FOXA1; CREB3L2; ZBTB18; ZNF652; ST18; TFAP2C; EGR2; TBX3; KDM5D; HES1; SOX9; ATF3; RELB