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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21300 Ibrutinib GSE70138 SKL.C Human 24h 0.37uM EID0064
Types Number Response transcription factors
Up-regulation 29 NR3C1; NFIL3; PPARGC1A; ID4; SMAD4; BTG1; RNF138; SSBP2; IRF8; NFIB; MXI1; PIR; ID3; ZFP36L1; NR1H2; ZFPM2; ERBB4; SMAD6; MAF; ATF5; TRIM29; MEIS2; SMARCA2; FOXO1; IFI16; CITED2; NFATC3; CREB1; BHLHE41
Down-regulation 17 HMGA2; NR2F6; MSX1; TGIF1; PAX6; NFATC1; EGR1; SOX9; ZNF217; NKX2-2; SUB1; HMGB3; MYBL1; YWHAB; ZEB1; POU2AF1; RELB
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