Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21289 Tyrphostin-ag-1478 GSE70138 SKL.C Human 24h 0.12uM EID0064
Types Number Response transcription factors
Up-regulation 125 HHEX; NFATC4; DNMT1; GMNN; DAXX; BACH2; HIC2; ZSCAN9; ELF4; CIITA; ZNF654; THAP7; NEUROD1; ZNF239; IRF1; MED15; CNOT3; MYBL1; HMGB1; PAX5; ZNF74; BRWD1; ESRRG; JUP; TGFB1; MYBL2; TCF3; SETDB1; USP16; ARID5A; SMARCB1; ZNF33B; TFDP2; NHLH2; CDK2; SATB1; EN2; PRDM2; ATN1; CBX6; FOXJ2; TTF2; SOX12; FOXF2; MEIS1; E2F3; TFAP2A; FOXM1; RB1; NKRF; ARNT2; LZTR1; HIRA; AES; CREB3; ILF2; RNF138; MAK; TCEA2; THRA; TCF25; HIPK2; ZNF423; TRIB3; DEK; BACH1; ZIC3; SUPT3H; TEAD4; ID1; TDP2; ZNF350; RBFOX2; SOHLH2; ZNF345; THAP10; ZNF232; RELB; TGIF2; TGFB1I1; TAL1; FOXE1; TERF2; COPS2; ZNF467; TCEA1; ZFP36L1; NFE2L3; ZFPM2; ZSCAN16; BCL11A; PBXIP1; ID3; ZHX2; PBX3; NR2F1; CBX7; ZBTB18; IRF6; EHF; ZBTB16; E2F8; STAT4; GTF3A; HDAC9; PAX6; ST18; MEIS2; HLX; LIN28A; SREBF1; ATF3; TXNIP; DLX2; SOX9; POU2AF1; ZBED2; PEG3; HOXB2; NANOG; MYT1L; PBX1; ZEB1; DACH1; WT1
Down-regulation 88 XBP1; CRK; RBM14; LMCD1; VGLL4; FOSL1; ARID4B; ZNF160; SMAD3; CTR9; ETV1; MED24; RBBP5; AHR; PUF60; ATF5; ZNF611; TSC22D2; SFPQ; ZKSCAN1; ZNF426; ZNF721; NFYA; BAZ2B; MED6; SATB2; ZBTB1; KAT6B; SMAD1; PIAS3; IRX5; TMF1; ZMYND11; ATF7IP; CARM1; SIX1; ZMYM2; NRBF2; PREB; SMARCD3; MED1; TRRAP; C1QBP; DDX5; HSBP1; TAF10; HOXC6; BMI1; ASCL1; DNAJC1; CITED2; PSIP1; BATF; CARHSP1; EYA2; NCOA1; TBL1XR1; CREB3L1; SIX2; TRIP6; HTATIP2; HMGN3; BCLAF1; PLAGL1; BAZ1A; NR1D2; FOXC1; ZEB2; EGR3; ZBTB38; DMTF1; NR2F2; ZNF652; YWHAB; FOSB; ZBTB20; NR1H2; PPARG; MSX1; IFI16; KLF6; ELF5; TOX3; ELK3; CREB1; NFATC3; GATA3; SUV39H1