Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21251 Tivozanib GSE70138 SKL.C Human 24h 0.37uM EID0064
Types Number Response transcription factors
Up-regulation 48 RBBP5; HOXB5; MDM4; SUPT3H; SATB1; CREB3; PBX2; HOXB6; HOXB7; E2F2; TBX21; MTA2; EYA2; TOPORS; HHEX; LPIN2; ZNF329; FOXI1; MDM2; TBL1X; PIAS3; AR; TRIM16; VDR; SAP18; OVOL2; JUP; ZNF83; GATA2; STAT2; SOX17; ESR1; PLAG1; LITAF; MECOM; STAT4; FLNA; MEIS1; NFAT5; TGFB1I1; SOX11; GTF3A; HOXB2; MAFB; TSC22D1; EHF; BCL3; NFATC3
Down-regulation 26 PSMC3; TFCP2; HMGB2; ZFP36L2; ID1; STAT6; GATA6; CENPF; RAN; HEY1; BASP1; ID4; BAZ1A; CREB1; YBX3; HMGN3; ID3; HLF; KLF6; KLF10; NKX3-1; LEF1; SOX9; TXNIP; ZNF652; HOXC6