Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21250 Tivozanib GSE70138 SKL.C Human 24h 1.11uM EID0064
Types Number Response transcription factors
Up-regulation 19 TLE4; CCNA2; TSG101; IRF4; RELB; ID1; MNT; POU2AF1; ID3; SREBF1; ZBED2; TBL1X; GATA2; KLF6; ZEB1; NR1H2; MAGED1; TBX3; EGR2
Down-regulation 32 THAP11; VGLL4; MYBL1; CDK2; ING4; FOXM1; HEY2; NEUROD1; YEATS4; BTG1; SMAD3; TOX3; TBL1XR1; TERF2; FOXC1; CALR; ZNF551; ERG; TSC22D1; IRF6; TOB1; MBD2; INSM1; SOX9; NR2F2; IRX5; ELF5; ZIC1; NFATC3; HOXC6; SUV39H1; E2F2