Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21235	Mitoxantrone	GSE70138	SKL.C	Human	24h	10uM	EID0138

Response Information :

Types	Number	Response transcription factors
Up-regulation	61	FOXM1; PHOX2B; MYBL2; MECP2; PSMC3; NFKBIB; TCF21; ZNF835; ESRRG; VGLL1; SP140L; ZNF75D; POLR3C; ACTL6A; SOHLH2; NR1I2; KLF7; VPS72; AEBP1; PPP1R13L; MNDA; MYCL; NR5A2; TOX; HAND1; CD3D; BHLHE41; EHF; SSBP3; FOXN3; GRHL2; KLF5; POU2AF1; HIRA; INSR; TTF2; TRIB3; ELF5; E2F8; RBPMS; PAWR; PBX3; FOXF1; DLX2; ISL1; HDAC9; TAL1; NKX2-1; RBBP8; IRF6; ETS1; KDM5D; MECOM; SOX11; ZFPM2; BCL11A; MEIS2; ZBED2; SNAI2; ATF3; ID1
Down-regulation	82	MYC; TLE1; BHLHE40; MEF2C; CDK7; PARP1; NFKBIA; ARID4B; HMGA2; SOX4; CRK; FOSL1; NFIL3; ZBTB18; BAZ2B; VEZF1; JUN; XBP1; PPARG; AHR; FOXO4; TSC22D1; SUV39H1; BRD8; KAT8; VGLL4; NUP62; BTAF1; HOXA5; NRIP1; BCL6; SIX1; NFKB1; TBP; RARA; ZNF189; THAP11; FOXJ3; EGR3; TRIP6; PATZ1; BTG1; MED1; TGIF1; KDM2A; TAF1D; APEX1; JARID2; ING3; NR4A2; ERBB2; CHD9; ZBTB11; ZNF84; FOXC1; PCGF2; MAGED1; HSF2; KLF2; NR2F2; BASP1; DNMT3B; SMAD3; CEBPD; FOXA1; ZBTB1; CTBP2; ZNF91; TOX3; ELK3; JUNB; CHD7; IRF4; ZFP36L1; ZNF160; SMAD1; FOSB; HEY1; PEG3; MYB; MTF2; GATA3