Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21189	Regorafenib	GSE70138	SKL.C	Human	24h	10uM	EID0138

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	PPARG; DDIT3; NFIL3; RELB; ATF4; NFKB1; BANP; CDK8; TLE1; NFKBIB; TRIM29; HIVEP2; TP53; CEBPG; BHLHE41; PURA; CRY1; CLOCK; KLF5; ING3; TRIM24; CREB3L2; CREM; BAZ1B; NR4A3; VGLL4; CRYM; CREB3; EDF1; RNF6; ZNF331; ZMYM2; PAX6; ELF5; EN1; DACH1; ZSCAN31; PHIP; INSR; ATF3; TRIM16; PPP1R13L; NR1D2; CEBPA; NANOG; OSR2; BIRC2; ZNF165; CD3D; TCEA1; BATF3; EHF; ZNF264; IRF1; HEY1; TRIB3; MAF; PBX3; SATB1; ERG; IRF6; ETS2; RBPMS; INSM1; RORA; PEG3; EMX2; BASP1; NFATC3; ZIC1
Down-regulation	64	HMGA2; MYC; MYCBP; SMARCD2; MEF2C; FHL2; RARA; ETV1; EGR1; FOSL1; YWHAB; ZNF467; HMG20A; NFIC; EGR3; LOXL2; BCL10; STAT6; APEX1; CBFB; ELK3; PCGF3; KLF2; TGFB1; ZFP36L1; MAFB; SFPQ; HMGA1; SMARCE1; HOXB2; ZMYND8; ARID1A; PRRX1; SMARCC2; TRIM22; CDK9; NCOR2; CENPF; SIX1; ZNF512B; MYRF; FLNA; BCL6; CCNE1; HIC2; CCNA2; SMAD3; PCGF2; BRD4; CBX6; SOX11; PAX5; TFAP2C; ZSCAN18; NR2F1; HOXB7; HIRA; PBX1; HOXB6; CREB1; EGR2; SOX2; GATA3; E2F2