Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21028	Saracatinib	GSE70138	SKL.C	Human	24h	10uM	EID0138

Response Information :

Types	Number	Response transcription factors
Up-regulation	103	RELB; HDAC3; ARID5A; ZNF358; PCBD1; SND1; SREBF2; KMT2B; MKL1; HOXB1; ESRRG; PRDM1; ARID3B; STAT5B; SRCAP; E2F1; ZNF768; EZH1; ZNF335; DLX5; MBD3; ZBTB7B; TFDP2; CERS4; TAF6; NR0B2; CD3D; CNOT3; NFKB2; CIC; HOXB13; SP2; TGFB1; MED12; PROP1; HDAC1; ZNF205; FOXJ1; RING1; KDM5C; KLF7; MED15; HOXC13; BARX2; TRRAP; PBX2; PRDM14; PRKDC; CIZ1; ZNF671; POU2F2; ZMIZ2; KLF13; GTF3A; RUNX3; LEF1; SIRT7; RARG; MDFI; HSF1; MXD4; TOX; PBXIP1; AEBP1; DEAF1; PHF1; TFAP2A; ZNF423; NFE2L3; ZNF711; SPIB; AR; RNF141; WT1; HMGN3; TCF7; CREG1; CBFA2T3; E2F5; INSR; ATN1; BCL3; TFEB; MYRF; RNF10; CEBPA; ZNF117; POU4F1; ZNF331; MYBL1; BRD4; DLX2; FOXF2; NFATC3; ZNF589; EHF; IRF6; TRPS1; DMTF1; NR1H2; MSX1; ZFPM2; MEIS1
Down-regulation	146	ATF1; MYC; HIF1A; FHL2; CEBPB; CRK; HMGA2; BHLHE40; CDK7; MEF2C; TAF9; FOSL1; ARID4B; HMG20B; HDAC2; XBP1; IRF2; NUP62; VEZF1; TCF12; KDM5D; MED6; NFIL3; IFI16; ZNF143; ZNF302; APEX1; CEBPZ; GABPA; DEK; AHR; MED7; KLF2; TOB1; ZNF146; TFAM; NFIB; NFYA; RBBP4; MAX; SOX4; MED1; BCL10; ZNF217; ZBTB1; ERBB2; TGIF1; ZNF263; NFKBIA; REST; DPF2; ZBTB11; MED20; BAZ1A; SMAD1; HOXA5; TBL1XR1; BCL6; SIX2; VGLL4; PROX1; DDIT3; SMAD4; WWTR1; ELF1; BRD3; ADNP; SP3; C1D; SATB2; RBPJ; ZNF24; RNF111; NR2F6; RNF138; MED17; TBPL1; NFE2L2; BACH1; PCGF2; BBX; CLOCK; KAT8; ZNF189; KLF4; ING3; TBP; TTF1; ELK3; SAP30; TRIM22; SMAD2; KLF10; PMS1; CBX3; RUNX1; SIX1; SMAD3; TRIM32; CDC5L; JAK2; CBFB; BTG1; ZMIZ1; HMGB2; IRX5; IL16; RLF; PBX1; E2F6; JUND; SOX11; CCNA2; MNAT1; CTBP2; NCOA4; HOXA10; NRIP1; NR1D2; ZBTB38; HOXC6; NKX3-1; CREM; HSF2; BMI1; ABL1; MED21; ID3; FOSL2; ZMYM2; ST18; ZNF232; TSC22D2; SUB1; ATF5; ZNF91; ETS2; EGR3; MAFB; TOX3; HOXC10; ZFP36L2; ASCL1; HHEX; ATF3; GATA3