Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20993	Tie2-kinase-inhibitor	GSE70138	SKL.C	Human	24h	3.33uM	EID0137

Response Information :

Types	Number	Response transcription factors
Up-regulation	62	EZH2; RHOA; PMF1; NFIC; IKBKAP; PIAS1; ZNF500; FOXI1; ZNF282; LZTR1; HMGXB4; ZNF629; RREB1; MLXIP; CHD8; IRF3; SIRT7; NFIL3; MED13; FOXM1; SETD2; TEAD4; CUX1; ZNF337; E4F1; AR; ZNF580; FOXA2; CBX4; TAF6; ZNF12; ARID1A; PCGF1; ETV4; VPS72; RRN3; LEF1; PREB; FOXK2; EMX2; GTF2IRD1; SUB1; HOXA11; TRIM28; TGFB1I1; IRF6; TULP3; SIX2; ZNF263; RORA; TRRAP; ZNF107; HMG20B; MKL2; RBPJ; CRYM; FOXF2; TRIB3; ZFP36L1; MSX1; CALR; SMAD1
Down-regulation	91	XBP1; TSC22D3; TFDP1; USP22; DNAJC1; PSIP1; EPAS1; WWC1; FOXO4; COPS5; NRIP1; ARNTL; TBPL1; SMARCA2; ETS1; BBX; ZNF165; NAB1; TAF12; LMCD1; ZNF556; HTATIP2; FOSB; HMGN3; CRK; BAZ2B; PRRX2; ELF1; SP110; HIVEP2; SNAI2; HOXA1; BASP1; TEAD1; PPARGC1A; HOXC6; ATF3; ZEB2; CREB1; ZNF281; ING2; PKNOX1; NR1D2; HSBP1; KLF3; ASCL1; GTF3A; FOXJ1; KLF6; ELF3; PRRX1; PEG3; RBBP4; BHLHE41; TSC22D1; CREM; ZBTB18; LOXL2; KLF4; TAF9B; KLF2; MXI1; TOX; NFATC1; ID1; NFIB; IRX5; KLF10; JUND; TOB1; TFDP2; HEY2; ERBB4; ZNF721; ZFPM2; JUNB; TCF4; NKX2-2; ZSCAN18; ZNF423; HOXB7; TRIM29; EYA2; DAXX; ID4; ZBED2; NR4A2; AHR; TBX3; HOXD1; NFATC3