Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20962	Regorafenib	GSE70138	SKL.C	Human	24h	10uM	EID0137

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	KDM5A; NFIL3; DDIT3; NFKBIB; NFKB2; PGR; ATF4; ING3; BIRC2; FOXM1; AFF1; HMGN3; CCDC59; RCOR3; PHF1; ZNF10; CEBPG; DNAJC1; SAP30; IRF4; NR2C1; FOXJ2; NFE2L1; HEY1; MITF; STAT5A; HSF2; PIAS2; DBP; ZNF331; MTDH; DEK; TRIM24; RORA; CCNH; ATF3; POLR3C; ELF1; REPIN1; NR1D2; PNRC1; ADNP2; MED15; ZNF263; BRD2; BANP; TRIM33; TRIB3; ISL1; THAP10; TCEA1; COPS2; TLE1; NFAT5; MXI1; TULP3; BRD4; NFKB1; PIR; SOX2; TXNIP; RBBP8; CREB3L1; ST18; ZIC1; ASCL1; ZNF83; FOSL2; ZNF302; HDAC9; TOB1; PBX3; HLTF; FOXF1; BHLHE41; VGLL4; RBPMS; ZNF423; TRIM29; SOX11; EYA2; BTG1; NKX3-1; SMAD1
Down-regulation	73	HMGA2; MYC; MYCBP; FHL2; RUVBL1; EGR1; MYBL1; SMAD3; WWC1; SMARCD2; NFE2; MEF2C; SNAI2; HOXB2; RUNX1; NR2F1; EPAS1; FOXG1; E2F3; SMARCC1; EGR3; SSBP2; HOXB6; HOXB5; HIPK3; HIC2; ERBB2; E2F5; ZBED4; REST; FOXC1; HOXC6; ZNF281; MEIS1; LOXL2; NFATC4; HOXB7; SMARCC2; RBM14; CNOT6; NPAS2; WWTR1; HDAC1; PRRX1; DAXX; HMGB3; ZBTB16; CHD7; TLE4; HSBP1; PAWR; KLF6; YWHAB; TAF9B; NFE2L3; ELF3; FLI1; FOSL1; WT1; DLX2; ELK3; CITED2; PBX1; TFAP2A; TFAP2C; KLF10; BCL11A; TBX3; LEF1; NFATC3; BASP1; ID1; GATA3