Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20919	Alectinib	GSE70138	SKL.C	Human	24h	0.12uM	EID0137

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	ADRB2; PHIP; ARNTL2; HR; ZNF571; TERF2; SNAI1; PGR; SATB1; PPP1R13L; SRCAP; ERF; MYCN; HTATIP2; PAWR; TCF3; SKI; NEUROD1; BCL11B; SOX18; CBFA2T3; CERS6; E2F8; CBX4; POU4F1; MYB; IRX4; TBX1; EHF; PHOX2B; REL; GATA3; JUNB; JUP; HIRA; ZNF512B; KLF11; NFE2; FOXA2; ELF5; TGFB1; ZNF623; SAP30; E2F5; MITF; ESR1; ZKSCAN1; NR5A2; PITX1; NFIB; VDR; TCF7; ZEB1; ZNF165; ZBED2; NR1H3; IRF6; TRIM16; TFDP2; ZBTB20; SMAD1; ZFP36L2; BTG1; DLX5; CD3D; LEF1; ELK3; HOXC6; NFATC3; TFAP2C
Down-regulation	85	CDK2; TBL1X; NR2F1; FOSB; PKNOX2; ZBTB18; IRF5; ZNF516; EDF1; ZNF148; TRAK1; CDYL; ZZZ3; UBP1; ID2; FOXG1; CITED1; HIPK2; TULP4; CHD7; BCL10; MEOX1; PBX1; ZNF587; PHF1; PDLIM1; SMARCD3; NCOA6; ASCL1; DDIT3; TRRAP; MKL2; PSMC3IP; NCOR2; CRY1; ZEB2; ETS1; KDM2A; NPAS2; HEY1; RARA; TFDP1; RERE; ZNF22; CEBPG; BMI1; RXRA; TCF21; RFX5; ATF4; ZFP36L1; ZNF423; MAGED1; EGR3; AFF1; ZNF432; PBX3; NR2F2; SNAI2; HMGB3; BRD4; ZFPM2; SOX11; MXI1; MECOM; TLE4; ZNF532; NR4A3; CREM; STAT6; CEBPD; MYRF; SIX1; CREB3L2; MEIS2; IFI16; ID4; EGR2; BCL3; MAFB; BHLHE41; VPS72; ZBTB16; NR3C1; TBX3