Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20918	Alectinib	GSE70138	SKL.C	Human	24h	0.37uM	EID0137

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	IRF5; NFIC; GCFC2; MYT1L; ELF3; PPARGC1A; NFYC; CHD3; MNAT1; HLF; NAB2; DNMT3B; STAT6; NR1I3; DEAF1; MEF2A; KDM5D; DBP; TGFB1; HOXB13; TAF4; RERE; SUPT6H; DDIT3; FOXA2; TLE2; NR0B1; ATN1; SAP30; CTR9; HMGN3; SATB2; PLAGL2; MED1; MAX; CITED2; TOX; RUNX3; MSX1; CRYM; RBPMS; NR2F1; SPIB; NR2F2; CENPF; CALR; ETS2; WT1; PAX6; ELK3; GATA6; TRIP6; EYA2; ZNF91; SIX1; HOXD1; EMX2
Down-regulation	73	HOXB2; UIMC1; EYA1; TCF4; LEF1; SOHLH2; CEBPD; ZEB2; PHF1; WWC1; MEOX2; KAT2B; ARL2BP; SIX2; WWTR1; FOSL2; TCF12; ZHX2; HLX; SNAI2; GTF3A; ZNF302; MEIS2; AEBP1; ZNF83; TOX3; POU2AF1; ZSCAN18; MNDA; BTF3; ZEB1; YBX3; TCEB2; MXI1; MYBL1; ZNF410; RORA; NCOA1; RUNX1; ZKSCAN1; MKL2; TLE4; HHEX; ZNF24; ASCL1; TGFB1I1; HTATIP2; PBX1; PBX3; MYCN; TRIM29; THAP11; PFDN5; OLIG2; TFAP2A; MAF; TRIM16; FLI1; PITX2; BASP1; MEIS1; MAFB; BACH2; HEY1; TWIST1; DAXX; RBPJ; FOXF1; TBX3; PEG3; HOXC6; NFATC3; ID4