Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20917	Alectinib	GSE70138	SKL.C	Human	24h	1.11uM	EID0137

Response Information :

Types	Number	Response transcription factors
Up-regulation	51	CCNA2; SUV39H1; ELF3; ETV1; PIR; NR2F1; HDAC1; NCOA6; RNF6; TBPL1; AIP; TBX2; WWTR1; PCGF1; ZZZ3; NPAS2; FOXC1; RUVBL2; FOSL1; SOX9; TRIM27; FOS; HMGB2; TOX; AHR; SREBF1; FOXJ1; LPIN2; MTA1; BATF3; NKX3-1; HMGA1; NCOA2; NR1H3; FOXG1; ETV5; HOXB7; FOXF2; MEOX2; HMGN3; ELF5; ASCL1; FOXF1; SPIB; NR1H2; EYA2; SOX2; RUNX3; TFAP2C; MECOM; BHLHE41
Down-regulation	95	FOXO1; CUX1; E2F5; CERS6; TXNIP; FOXN3; BHLHE40; ZNF665; SRCAP; TERF2; ZMYND11; MED13; ZNF426; SOX11; CRK; EPAS1; ZKSCAN7; ZNF652; CHD3; RNF138; KLF9; ZNF329; ATF5; TCF4; SIRT2; KLF11; ADNP; HIVEP1; ZNF253; HIVEP2; KMT2A; ERBB2; CDX1; ZHX2; NAB1; ZNF124; BTF3; VGLL4; NR3C2; BACH2; NFATC4; IRF8; PCGF2; ZNF239; PBX1; INSR; MNT; MEF2A; YAP1; CREB3L2; LOXL2; ZNF430; ID3; SMAD2; MYCN; PRDM2; NCOA4; HOXB2; NFATC1; ZNF165; BCL11B; HDAC4; CHD9; MAF; NR1D2; ID1; NFE2L3; HIPK3; TRIM22; KLF10; LMCD1; SMAD1; ZNF423; BTG1; ZNF721; HEY1; BNC2; ZIC1; PEG3; TLE4; CUX2; BCL11A; LEF1; POU2AF1; TRIM29; ZFPM2; ESR1; GATA6; THAP11; CITED2; ZFP36L1; ZFP36L2; MSX1; MAFB; NFATC3