Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20890	Dabrafenib	GSE70138	SKL.C	Human	24h	0.04uM	EID0137

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	E2F2; KDM5A; NHLH2; NEUROD1; TAF9B; SPI1; EN2; MTA2; KDM5D; NFX1; NFAT5; ZNF124; ASH2L; ETV6; MYT1; MDM4; THRAP3; EN1; ORC2; ZNF528; NFIB; MLX; BLM; VGLL1; NR1D2; MYT1L; PROX1; FOSL2; ESRRG; STAT4; SATB2; INSM1; ELK3; CTNNB1; ZNF217; GTF3A; WWTR1; MAFB; ZFP36L2; PAX6; CREM; CUX2; HMGN3; NKX2-2; WT1; TXNIP; TGFB1; DLX5; SOX9; ZBED2; ATF3; ATF5; ZIC1
Down-regulation	54	HDAC3; PAWR; TCF21; TEAD3; IRF9; SIX2; TOX; SPDEF; KLF4; PIR; SMAD7; KLF6; RBBP7; PSMC3; KLF7; MAFF; HOXB2; ID2; NPM1; TCF7; HMGB2; NR2F1; FOXD1; ERBB2; NR2F6; RUNX1; SIAH2; ZNF160; FOXF1; MAF; SOX2; TRIB3; KLF2; HEY1; CREB3L1; TOX3; HOXC6; ZNF165; HOXC10; SNAI2; EGR3; HOXB6; TCF4; ZEB2; ZNF91; BASP1; BTG1; EGR2; TWIST1; NFATC3; TBX3; MYBL1; GATA3; RELB