Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20802	Saracatinib	GSE70138	SKL.C	Human	24h	1.11uM	EID0137

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	IKZF1; NHLH2; TBX21; RREB1; HESX1; SP110; ZNF264; CHD2; SP140; KLF13; PIAS1; HIRA; SP4; NR3C2; CBX7; IRF6; FUBP1; ZNF117; AFF2; ARID5B; IFI16; NEUROD1; TGFB1I1; E2F3; ZIC3; RUNX3; INSM1; ZNF219; KLF1; NAB2; SP140L; ZNF75D; BACH2; NR5A2; LHX2; DBP; TAF4B; ZFP36L2; STAT2; CCNC; MDM4; HOXA5; MED15; VGLL1; MECP2; PAX6; ZBED2; TRIM29; GRHL2; TCF7; GTF3A; MEOX2; LPIN2; LITAF; TCEA1; FOXA1; CBFA2T3; HIPK1; SALL2; DAXX; PRRX1; STAT5A; FOXE1; ZNF124; ERG; FOXF1; STAT4; MXI1; SUB1; CREB3L2; KDM5D; SOX3; SSX1; ATF4; TP63; INSR; NR1D2; IRF1; ZNF107; ARNT2; EHF; HIC2; HHEX; MAFB; HBP1; NKX2-1; ZNF232; TFAP2A; VPS72; SHOX2; ELK3; HLF; SREBF1; CUX2; OSR2; DLX5; ATF3; IRF7; TRIP6; NR1H3; MEIS2; SOX9; LEF1; KLF10; MYRF; TFAP2C; CREB1; NFATC3
Down-regulation	58	MYCBP; ATF6; FOXO4; ZMIZ1; NCOA3; HDAC6; TLE4; ZBTB18; NEDD8; PIR; MEF2A; MED20; BCL6; NFE2L1; ASH2L; SFPQ; TOX3; MXD4; TAF10; SIX1; ING2; TP53; EDF1; NCOR2; SMARCA2; HTATIP2; RARA; TCF4; MED7; HSBP1; TULP4; TRIM28; HMGB3; ZNF532; KLF4; EGR1; CREB3L1; ZNF468; HOXC10; STAT1; RBPJ; SIX2; SATB2; MNAT1; CITED2; CENPF; IRX5; JUNB; ZSCAN18; TSC22D1; TBL1X; ZBTB38; PEG3; PDLIM1; TXNIP; EMX2; ID1; RELB