Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20782	Mitoxantrone	GSE70138	SKL.C	Human	24h	10uM	EID0136

Response Information :

Types	Number	Response transcription factors
Up-regulation	103	ESRRG; SUV39H1; FOXM1; RELB; KLF5; SSRP1; PLAGL2; BCL3; ELF4; MECOM; PPARG; BRD4; TAF6; HIPK2; ZNF45; ELF5; ZNF573; HOXB6; MBD2; RBPMS; PSIP1; TFE3; KDM5A; HDAC1; HLF; ARID4B; SSX1; RB1; CHD4; MLXIP; HMGA1; CREB1; ZNF33B; IKZF2; FOXG1; ZNF227; MITF; ASCL1; SF1; TOX3; FOXN3; PHOX2B; ATF7IP; NR3C2; POLR3C; ZNF652; NR2E1; NR1H2; MYCN; ZBED1; PPP1R13L; TEAD1; EN1; TFCP2L1; ZNF223; FHL5; NFIB; NFATC3; HAND1; INSM1; IRF1; WWC1; NEUROD1; SMARCA1; CDK2; TCF7L1; ARNTL2; CREB3L1; FOXA2; ID3; NKX2-2; E2F1; SATB2; RBBP7; NFAT5; SPDEF; TAF4B; MYCL; MED14; PBX1; TGFB1; VGLL1; NHLH2; EHF; PQBP1; ZBTB18; ZBTB38; PBX3; MYBL1; HOXB7; NFE2L3; NR1D2; ID1; MYBL2; BRIP1; ID4; HOXB2; LIN28A; MYB; SPIB; HIRA; MEIS2; KDM5D
Down-regulation	113	MYC; NFKBIA; CDK7; MEF2C; ZBTB11; FOSB; NKX3-1; JUN; FOSL1; YBX3; CHD1; MTF2; MTDH; IL16; EGR1; BHLHE40; NFIL3; MED17; KLF10; TAF9; CHD9; TAF1D; TSC22D3; XBP1; NLK; HMBOX1; TLE1; CCDC59; ZNF331; CTBP2; ETV5; ZFHX3; HOXA5; GLI3; NR2C1; ATF5; CRY1; PCGF2; DDIT3; BTAF1; HMGA2; ATF2; IRF7; RUNX1; ZBTB1; TSC22D2; FUBP1; MNT; SREBF1; AHR; UBE2B; CNOT2; CREBZF; PRMT2; TBP; NR4A2; MAFF; CDK8; ZNF12; JUND; BTG1; TGIF1; IRX5; ZMYM2; BCL10; EGR3; CEBPD; ZEB2; SMAD3; ZNF131; TRIM22; NR0B1; ZNF83; ZNF266; IRF4; MAFB; FOXC1; BASP1; KLF6; ASH2L; SIX1; ZNF512B; INSR; NPAS2; DNAJC1; EYA2; BRD8; TRIB3; SMAD7; BHLHE41; TLE2; SMAD1; WWTR1; SMARCD3; C1QBP; AEBP1; DDX5; ZNF217; ESR1; ZFP36L2; TBX3; VGLL4; MED1; JUNB; IFI16; HOXD1; TOB1; LEF1; WT1; HOXC6; TSC22D1; TRIP6; NR3C1