Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20657	Dabrafenib	GSE70138	SKL.C	Human	24h	3.33uM	EID0136

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	GATA3; GATA2; MED4; ATF1; NR2C1; SATB1; CCDC59; CREB5; NFKBIB; BAZ2B; CRY1; MYRF; SOX10; EZH2; MTF2; CBX3; SSX1; ISL1; PPARGC1A; PA2G4; MED7; HLF; MAFB; ZKSCAN1; PHF20; ALX1; STAT6; CDK8; GCFC2; ARID5B; PSIP1; NR3C2; HCFC2; TBPL1; PSPC1; PREB; ZNF248; RNF6; ZMYM2; ZNF236; TFAM; THAP10; JARID2; ZBTB24; NKX3-1; MITF; ATF2; ST18; DDIT3; BCL11B; TRRAP; SALL1; TBL1X; RBPMS; ZNF302; ZNF410; HSF2; HOXA10; HMGN3; HIPK3; DMRT1; SAP18; ZEB2; NFIB; STAT5A; CTNNB1; ZNF571; ENO1; RORA; ORC2; URI1; CITED2; ZNF266; MED20; AHR; MED21; EYA1; ZKSCAN7; DNAJC1; CUX2; ZNF443; ZNF529; STAT1; ZNF227; TOX3; PIAS2; SSBP2; DMTF1; GTF3A; BNC2; TAF11; DACH1; TBX3; HOXC10; PROX1; NKX2-2; MEOX1; ATF5; TWIST1; ZNF239; CEBPG; HOXC6; SMARCA2; CEBPD; AEBP1; MAGED1; ELF5; RAD21; NR4A2; ZBED2; MYB; TRIB3; INSM1; BMI1; WT1; NR2F2; ESR1; TSC22D1; TXNIP; TOB1
Down-regulation	75	PUF60; MEF2C; NR2F6; EGR1; NRIP1; SMARCD2; TFDP1; ID3; RUNX1; SMARCB1; RHOA; PBXIP1; ZNF274; SREBF2; FOXC1; MED13; MEIS1; NFKBIA; CREB3; PPARD; CERS6; PAX5; MXD3; ZNF444; KLF7; ZNF629; CENPF; PSMC3; TSHZ2; CREG1; ZFHX3; HOXB5; ENY2; HDGF; TAL1; BCL11A; ZNF219; SIX2; TRAK1; SOX9; HOXB2; NR2F1; SIX1; ID1; NFE2L1; WNT4; HLX; IRF9; BCL3; LOXL2; ZNF512B; RUNX3; VPS72; ZIC1; BASP1; KLF10; FOXF2; ELF4; DAXX; ETS1; MED1; PEG3; HIC2; TGFB1; SPIB; GMNN; PBX1; E2F8; TP63; HEY1; MEIS2; SOX11; BTG1; TRIP6; NFATC3