Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20576	Saracatinib	GSE70138	SKL.C	Human	24h	3.33uM	EID0136

Response Information :

Types	Number	Response transcription factors
Up-regulation	117	MECP2; KLF7; NR4A3; PHOX2B; CSDE1; MYBL2; PAX6; RING1; NFKB2; VPS72; EHMT2; FOS; ZNF136; SPI1; MYRF; MEIS1; LITAF; ESR1; BACH2; GATA2; IKZF1; CUX2; PSMC3; SOX2; ZNF816; HLX; AEBP1; EHF; WT1; CBX7; FOXM1; BHLHE41; ZNF264; SPDEF; TCF21; PRDM1; REL; HAND1; ZNF91; ETS1; ISL1; NR2E1; ZNF415; CDK2; HOXB13; INSM1; ZNF331; MAK; ZNF345; HIRA; SOX17; CARHSP1; SOX18; ID4; ZKSCAN1; MEIS2; BCL11B; ZNF75D; MECOM; PRDM14; NFATC4; SKIL; NR5A2; EPAS1; E2F5; VGLL1; CBFA2T3; PDLIM1; TCEA1; ZNF623; NR4A2; HDAC9; MEOX1; MYCN; ST18; NEUROG2; GRHL2; ZNF467; ID3; ZBED2; ATF3; FEZF2; FOXJ1; IRF6; ZNF589; FOXF1; TGFB1; TWIST1; ZFPM2; HIC2; NHLH2; MSX1; WNT4; GATA6; MYBL1; NEUROD1; SOX3; CALR; TCF7; ID1; MXI1; TRPS1; RBFOX2; HHEX; DLX5; ZNF423; ARNT2; ERBB4; KLF13; WWC1; E2F8; MNDA; DAXX; PBX3; HOXB6; OSR2; LEF1
Down-regulation	102	FHL2; CDK7; MEF2C; NFKBIA; ATF1; TBP; MYC; FOSL1; NUP62; SCAND1; PUF60; ABL1; ERBB2; ZFP64; HOXC10; XBP1; HMGA2; SIX1; ECD; ZMYM2; SMAD3; EED; NKX3-1; ZBTB11; RBBP4; SIX2; SNW1; HOXA5; NCOA4; PCGF2; CITED2; ADNP; KDM2A; MED1; SOX4; DPF2; ZNF189; MLX; TP53; CEBPZ; CTR9; YBX3; PPARGC1A; KLF2; HOXC6; TSC22D2; TAF1D; KAT7; MNAT1; SFPQ; NFYC; SMARCA2; ZBTB18; RBPJ; BMI1; SATB2; CREB3L1; BRD3; RBM14; DDIT3; KAT6B; TBL1X; CRK; VEZF1; STAT1; RFX5; TBL1XR1; BAZ1A; IRF2; ZBTB16; SAP30; PHF8; KLF4; AFF1; MAGED1; ING3; AATF; TRIM32; PPARG; TCF12; RUVBL2; KDM5D; DDX5; SMAD2; IRX5; APEX1; ARID4A; KLF9; BTG1; ELK3; MYB; ATF5; TRIM22; WWTR1; C1QBP; TRIP6; HTATIP2; JUNB; NR2F2; HOXB7; SUV39H1; TCFL5