Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20220	Jq1-(+)	GSE70138	SKL.C	Human	24h	0.37uM	EID0101

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	INSM1; ASCL1; FOXC1; SPIB; EGR1; NFX1; STAT4; SOX3; NR4A2; UBE2L3; TRIM33; TERF2; ID2; PAXBP1; MNX1; BCL11A; TSC22D1; MED15; LHX6; BANP; SOX4; CREB3; PHIP; CBFA2T3; MYT1; HR; SSBP3; ZNF10; OLIG2; BRWD1; TCF7; POU4F1; CHD1; PAX5; ZNF394; NR4A3; HIVEP2; ZBTB11; SMARCA2; JUNB; PQBP1; RAN; ARNTL; DDX17; ZNF536; REL; NR5A2; RNF138; LITAF; CREB5; KLF9; HOXA10; AGO2; NR4A1; THRA; FLNA; TOB1; HOXD1; CDK9; DBP; MED23; TOX; IRF6; RBBP7; NKX3-1; EGR3; ERG; ZKSCAN1; CREM; FOXL2; HTATIP2; KLF11; RUNX3; NFATC3; ZMYM2; INSR; CTBP2; KDM5D; SMAD7; TRIM29; HMGB3; TXNIP; ZFP36L2; MYBL1; EMX2; EHF; TOX3; BASP1; HMG20B
Down-regulation	79	HMGA2; XBP1; ZNF432; ELK3; ATF1; NR2F6; CBX3; LZTS1; TRIP4; MEF2C; HEY1; IFI16; TRIM22; TP53; TCF12; PRRX1; MTDH; ZFHX4; ZNF91; ZNF444; PLAG1; ZMYND8; RBFOX2; SUB1; BNC2; ZBTB18; YAP1; SMARCD3; AEBP1; PLAGL2; CBFB; RFXANK; TEAD4; TGFB1I1; MAFB; YBX3; CERS6; SOHLH2; GLI3; MED7; PCGF2; TWIST1; SOX11; CEBPD; ZNF267; ATF5; MEOX2; MEIS2; SMAD6; YEATS4; FLI1; PPARG; TCF4; VGLL4; BRD4; RBPJ; BCL6; MDM2; HMGB1; ZBED2; LOXL2; GTF3A; ZBTB38; ZEB1; ZNF721; ZNF532; RBPMS; MYB; ZFP36L1; ZFPM2; WWTR1; HOXB2; LMCD1; SNAI2; HMGB2; MECOM; POU2AF1; TBX3; CREB1