Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID20057	Dabrafenib	GSE70138	NPC.TAK	Human	24h	10uM	EID0132

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	RELB; PDLIM1; GATA2; HIVEP2; ERCC2; SMAD3; BRD3; CHD1; MYB; NFE2L3; PREB; IRF5; ID3; TBX3; LIMD1; MLX; MED13; ZNF22; TFDP2; YAP1; UBE2B; NR3C1; ASH2L; AFF1; TRIP6; ID4; PBX3; IRF2; ZEB2; STAT5A; TCF7; NCOR2; BHLHE41; CD3D; ZNF423; TEAD4; BMI1; ZEB1; ID1; ERG; RXRA; INSR; SATB2; GATA3; POU2AF1; MAFB; CEBPB; ZBTB18; ZNF217; ETS2; MYCL; ASCL1; TOX3; ELK3; BASP1; ERBB4; PSIP1
Down-regulation	60	TLE1; HEY2; DDX17; PAX5; LHX2; SMARCB1; FOXM1; CARHSP1; BAZ1A; CDK8; CHD4; JUND; CBX4; EMX2; AR; JUP; EHF; MEIS1; PLAGL1; ZNF580; GTF2I; RBBP7; TOB1; LPIN2; ZFP36L1; HOXA11; POLR2A; PAX6; ZMYND8; FOXG1; ZFHX4; EYA2; RNF6; TCEB2; PTTG1; BRD2; ZNF83; LOXL2; ZBTB16; BBX; FLNA; SOX11; FOXF2; SOX10; KAT2B; KLF9; TCF7L1; MKL2; BCL11A; INSM1; MAF; ZBTB20; TFAP2A; TOX; PITX1; TGFB1; ARNT2; MYBL1; NR1H2; NFATC3