Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID19940	Tie2-kinase-inhibitor	GSE70138	NPC.TAK	Human	24h	10uM	EID0131

Response Information :

Types	Number	Response transcription factors
Up-regulation	159	PIAS3; NFATC4; VDR; ARHGAP35; GLI2; AR; OVOL2; NAB2; NFIX; CREBL2; E4F1; ZFY; RBPJL; ESR1; TAF1C; MED23; TFE3; JUND; RBL2; BRD4; CREB1; HCFC1; ZNF573; WHSC1L1; GMEB2; NCOA2; VPS72; FOXO4; NR1H2; L3MBTL1; CHD4; FOXL2; WT1; KDM5D; TSG101; PITX1; ZNF467; CHD3; EHF; PIR; SP100; ATF6B; PGR; ZBED2; CEBPD; DYRK1B; TRIM22; MBD2; AFF3; CIITA; FOXA2; WNT4; TAF4; ZNF334; ZSCAN31; NFIC; RUNX3; ELF5; BARX1; ELF4; HIVEP2; CBX6; YWHAB; NSD1; MLLT1; NCOA3; ZMYND8; TFEC; SP140; ZNF394; POU4F1; FOXO3; ZNF205; ZNF282; ZNF165; STAT6; ZHX3; TRRAP; SCRT1; PPP1R13L; HOXA11; ETS2; FUBP1; IL16; DEAF1; ZNF512B; TP73; MXD1; MECP2; SKI; IFNB1; PBX2; ZNF33B; ZNF589; ZNF133; BNC2; ZNF224; PLAGL2; SREBF1; TBX1; NFKB1; WWP1; MSC; ASH2L; SRF; ZFHX3; ZNF516; PAX5; PLAGL1; CBX7; NR3C2; TSC22D3; CDIP1; IFI16; TLE2; GATA6; ZNF136; UBE2I; IRF4; REL; MKL2; RSF1; EGR3; RBBP7; NFE2L3; RBPJ; BCL11A; KLF9; VGLL1; TFAP2A; SMARCA2; PEG3; IRF6; SOX17; DLX5; KLF6; PAWR; POU2AF1; IRF8; SIAH2; CRYM; RFX5; KAT2B; MED21; SPIB; ELF3; NKX2-1; TRPS1; HLF; EMX2; TXNIP; ELK3; MYBL1; FOSB; MECOM; AHR; ID4; FOS; PSIP1
Down-regulation	149	NRIP1; HMG20B; IKBKAP; SOX11; ZMIZ1; BRD3; PSPC1; TTF1; CHD1; EDF1; RUVBL2; SPEN; ID2; ZNF202; ZNF423; THAP1; GABPA; PCGF1; ZNF22; DMTF1; GTF3A; ZNF232; MED27; PBX3; HSF2; NRF1; TAF9; SALL1; ATF4; FOXJ3; ISL1; ERBB2; ARID4B; HCFC2; SAP18; PMS1; NCOA4; ARID1A; ZEB2; CREG1; CBX3; TRIM32; UBE3A; BTF3; CEBPB; HOXA5; MLLT10; ZFX; MNAT1; ZNF32; HMGB1; PSMC3IP; ALX1; ING3; RXRA; TBL1XR1; ZBED4; CNBP; RNF4; APEX1; ABL1; KAT7; SSBP2; ING1; ZNF131; MYCN; ZNF711; TCF7L2; MTF2; DLX2; KAT6B; ZNF410; ID3; ETV5; ZMYM2; MED4; AGO2; RBM14; SMAD4; NR0B1; SATB1; USP21; MAGED1; ZNF593; MED17; CEBPZ; ETV4; TCF7; RBBP4; RREB1; USP16; ZFHX4; CEBPG; DACH1; PITX2; JUNB; TFAM; CHD7; ZNF551; BLM; SOHLH2; BMI1; TCF12; ZNF329; TCFL5; MED13; FOXN3; ZEB1; HEY1; LOXL2; MED1; SIX2; MAX; ST18; DDIT3; MLX; EYA1; INSR; AES; NKX3-1; VGLL4; SALL2; ZNF532; BACH1; SIM2; COPS2; TOX; TOB1; NR2F2; JARID2; ELF1; HMGN3; NPM1; BASP1; YBX3; HIRA; RUNX1; PTTG1; HOXB7; TBX3; HHEX; ZFPM2; ZBTB18; HOXC6; NR4A2; ID1; ZFP36L1; ZBTB20; SOX9