Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID19910	Regorafenib	GSE70138	NPC.TAK	Human	24h	10uM	EID0131

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	HTATIP2; CEBPG; ATF4; TSC22D3; TRIB3; CDX1; TFEB; XBP1; HOXB9; ERCC2; DDIT3; BTG1; ATF5; KMT2A; SATB2; ZNF23; WWC1; NR2C1; ZNF215; ZNF195; JUN; ETS2; IRF8; FOXO3; MZF1; CTBP2; KLF6; CEBPB; ZNF165; YBX3; ARNTL; CERS6; PAWR; MED24; THAP4; CDX2; KDM4C; NCOR2; TERF2; GTF2IRD1; ATOH1; CUX1; INSR; ZNF516; TFCP2L1; TBL1XR1; MYCL; TFDP2; REPIN1; MLLT10; ELF3; CBFA2T3; MYB; PHIP; DACH1; SIX2; HOXB5; IRX5; MLXIP; SIM2; FOSL2; NFATC3; GATA6; NCOA1; PAX5; CBX6; CREB3L1; IRF6; OSR2; ZNF532; DNMT3B; AEBP1; ID1; MED13; FOXA2; RBPJ; PBX3; EHF; LITAF; NR4A2; RUNX3; ATF3; EMX2; BASP1; ESR1; AHR; HOXC6; PSIP1
Down-regulation	92	ETV1; HMGA2; GMNN; IKBKAP; HES1; ZNF512B; CDK2; EGR1; ETV5; IFI16; GABPB1; MAGED1; SOX11; CENPF; RBBP7; SP110; CALR; ZNF654; NONO; EGR3; BAZ1A; CCNA2; ZNF257; CBFB; PFDN5; DEK; ZNF93; NEUROD1; PEG3; SMAD6; SSBP2; SIX6; HHEX; VGLL4; EN2; IRF2; PRRX1; ST18; TFDP1; HOXB2; ELF1; DDX17; WWTR1; CCNE1; SMARCA1; NKX3-1; FOXM1; LHX2; TAF9B; MAX; TRIM24; TCF12; PLAG1; GTF3A; UBE2I; E2F8; ELK3; ELF5; CARHSP1; NR0B1; HEY1; RERE; TGFB1I1; MAFB; BBX; PBX1; RNF6; NR2F1; ID4; ZFPM2; PTTG1; BCL6; HLF; SOHLH2; BMI1; LIN28A; ZIC1; JUNB; MEIS2; SSX1; JUP; ZNF91; CREM; SOX17; TLE4; NANOG; RORA; LOXL2; KDM5D; LEF1; E2F2; GATA3