Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID19482	Belinostat	GSE70138	NPC.TAK	Human	24h	3.33uM	EID0096

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	EGR1; FOXO4; MYCBP; TGFB1; CREG1; SIX5; NR4A1; JUNB; SETD3; KDM5A; DLX4; SUB1; STAT1; CREM; CCNH; ETS1; MAZ; KLF2; ZNF205; SAP18; DRAP1; FOSB; HDAC1; RUVBL2; CTR9; LYL1; PHF1; HMG20B; SND1; IRF3; HSBP1; TRPS1; ARNTL; CDK9; WWC1; COPS5; YBX3; JUN; PRKDC; MXD1; KDM4C; BCL11B; SMARCD3; BBX; CEBPB; ENY2; TOB1; TCF7; NR4A2; SIX1; ID2; IRF7; MAF; IRX5; NFIB; NR1H2; ETS2; CRY1; LMCD1; NR3C2; BCL3; PITX1; RNF141; NPAS2; WWTR1; SMARCA2; SSBP2; ZNF331; MITF; MXI1; MYBL1; HHEX; FOXC1; FOSL2; FOXN3; HTATIP2; BASP1; ATF3; CD3D; FOS; MAFB; KLF5; HOXC6; PSIP1
Down-regulation	170	HMGA2; PCBD1; SMARCA4; NUP62; SALL1; EZH2; MTA1; TCERG1; BRIP1; NFKBIA; ZBED1; ZNF84; CCNA2; FHL2; SOX11; MYBL2; PHF2; ETV1; TP53; ATF1; TCF12; SFMBT1; SETDB1; NFYB; GABPB1; ZNF529; SP2; ZBTB1; ZNF227; TSC22D3; REPIN1; MAGED1; PATZ1; MED17; ZNF22; MED12; WHSC1; PKNOX1; HDGF; ZNF140; BRCA1; HDAC6; PLAGL2; WDHD1; ADNP; ZNF282; RFX7; RSF1; BPTF; MYCN; SALL2; ZNF232; RNF138; ZNF711; HMGB3; DDX5; ZFP64; ASXL1; MED1; DPF2; ZNF195; SCMH1; MLLT10; GLI2; TAF9B; TTF2; NCOA6; ZNF117; ZNF146; VPS72; CUX2; FOXM1; APEX1; ZNF273; SMARCA5; YEATS4; ZIC3; ERBB2; ID3; ZNF107; ZNF551; BAZ1A; ING3; TCF4; ZNF141; ZNF3; GTF2I; MECOM; ABL1; PPRC1; ZHX2; HIPK2; SIX3; PCGF2; NCOA2; SMARCC2; ZNF43; MED6; ZNF93; MEIS2; ZMYND11; RXRA; HMGB2; ZBED4; E2F8; RBPJ; TCF7L1; AEBP1; MED24; ID4; TGIF2; SMAD2; STAT5A; ZNF423; KLF7; HOXB6; E2F5; ZNF532; TGIF1; PIR; YEATS2; ZNF32; NEUROD1; SMAD3; BATF; MKL2; MYCL; PLAGL1; ZEB1; SOX17; ID1; DLX5; CNOT2; IRF4; IRF9; ZFP36L2; ZNF512B; ARID5B; NFKB1; TBL1X; SMAD1; LEF1; HLF; TBL1XR1; ZFP36L1; TRIM22; FOXF2; KLF9; ZFHX4; ASCL1; EYA2; BCL6; ST18; HOXB2; KDM5D; CHD7; XBP1; IFI16; KAT6B; PBX3; TOX3; POU2AF1; NRIP1; HOXB7; BHLHE41; TXNIP; SUV39H1; NFATC3; PPARG; E2F2