Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID19332	Mk-1775	GSE70138	NPC.TAK	Human	24h	1.11uM	EID0096

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	ARNT2; HOXA10; TGFB1; TFAP2A; CALCOCO1; ZNF467; IRF9; SRCAP; HLX; CREB3; KLF3; CERS4; KLF11; TRIB3; ST18; PSMC3; CDIP1; TCEA1; ZNF580; DAXX; NFE2L2; FOXF2; ZIC3; MAFF; TULP3; ELF4; IRF8; ZNF264; YBX3; ZNF239; ZEB1; CAPN15; LOXL2; DNMT1; AES; NFE2L3; TAL1; ZFPM2; MED15; TEAD4; MXI1; MYRF; TGFB1I1; BACH1; INSR; CBX7; SALL2; IRF6; ZNF12; PRRX1; PAWR; GATA6; UBE2B; PBX3; NEUROD1; MYBL1; CITED2; HOXB2; TLE2; HIRA; BNC2; JUP; OSR2; CEBPD; FOXN3; INSM1; HDAC9; HHEX; PAX6; MEIS2; FOXF1; ZFP36L1; MAFB; LITAF; ERBB4; POU2AF1; AEBP1; BHLHE41; ATF3; SNAI2; SOX9; MNDA; WT1; PSIP1
Down-regulation	67	EZH2; NR2F6; NUP62; RFX5; BRCA1; ETV1; WHSC1; CCNA2; CTR9; HLTF; PIAS2; MAGED1; SFPQ; BMI1; HMGB3; DNAJC1; RBBP4; NR2F2; BRD3; POLR2A; TRRAP; ITGB3BP; DDX5; SMARCA1; VGLL4; ZNF226; SIX1; HNRNPD; DPF2; SMARCE1; CITED1; SMARCA5; SIAH2; TSC22D1; CENPF; CREBZF; PCGF2; MYB; BLM; BBX; SIX2; BATF3; CHD1; LPIN2; PURA; BAZ1A; PTTG1; RBBP8; NR1D2; TGIF1; AFF1; ENO1; IRX5; RBPMS; CTNNB1; MSX1; ZMYM2; ASCL1; HOXC6; FOSB; LEF1; TBL1X; SUV39H1; BCL11B; CD3D; NFATC3; PPARG