Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID19147	Mk-1775	GSE70138	NPC.TAK	Human	24h	1.11uM	EID0095

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	CBX7; ERBB4; TSHZ2; NFE2L2; ELF4; OVOL2; ZSCAN16; ZNF264; ZNF623; ZNF557; PDLIM1; BRWD1; RUNX1; TGFB1; HBP1; MECOM; HOXB2; FOXF2; CBFA2T3; ZNF34; ZKSCAN4; ZNF345; RARG; TGS1; MED15; CNOT3; NR1H4; ARNT2; NPAS2; PPARA; UBTF; TP73; ZNF155; CAMTA2; HSF1; SIX6; AES; TRIM33; BNC2; TTF2; ZNF74; HOXB1; JUNB; LHX3; HIVEP1; CIITA; SOX3; ST18; FEZF2; MAK; RORC; DAXX; ZNF180; THAP7; CREB3; TCEA1; CALCOCO1; SOX18; TAL1; NR1I3; TP63; TFAP2C; CCNH; LOXL2; ZNF467; TRIB3; TCF21; GATA6; MBD2; MYBL1; CRYM; IRF6; ZNF12; IFI16; SPDEF; MAFF; ELF3; HOXD1; PRDM2; HIPK1; BHLHE41; TDP2; NR3C1; YBX3; STAT6; ESR1; NR5A2; KLF13; MEIS2; ATF3; SOX17; ZHX2; DLX5; SMAD7; NFE2L3; EPAS1; ZNF512B; ZNF267; FOXF1; SKIL; PRMT2; MXI1; GFI1B; HEY2; NFATC4; HDAC9; CBX6; TFAP2A; NCOA2; TGFB1I1; RORA; POU2AF1; PAWR; TRIP6; MYRF; MNDA; CEBPB; ZNF331; BCL11A; JUP; IRF9; SHOX2; INSM1; KLF10; ZEB1; EMX2; HMGA1; INSR; BTG1; KLF5; TOB1; TRIM29; NR1H2; MAFB; CEBPD; SOX9; ZFPM2
Down-regulation	98	PARP1; SUV39H1; NR2F6; ETV1; EZH2; NUP62; HDAC2; HSBP1; RBM14; CCNA2; NCOA6; DNMT3B; HMGB3; BRD3; SFPQ; ZMYND11; RNF141; EDF1; CBX5; MED21; RBBP7; BMI1; FOXM1; POLR2A; ITGB3BP; BLM; NEDD8; CITED1; RBM39; TAF10; BAZ1B; BRCA1; CENPF; BCLAF1; HDAC1; YAF2; RCOR3; WHSC1; SSRP1; SMARCE1; MYCBP; MAGED1; SIAH2; ZNF93; MED20; PTTG1; RNF14; GATAD2A; HNRNPD; CTR9; ZBTB1; ZNF43; BRD8; CBFB; TAF9B; TBL1X; ZNF443; RAN; NPM1; UBP1; YWHAB; PIAS2; CTNNB1; RBBP4; ING2; IRX5; DMTF1; MSX1; CHD7; TRRAP; BATF3; AFF1; CD3D; CRY1; C1QBP; HMGB1; IRF4; HLTF; BATF; MYCN; HOXC6; HMGB2; EYA1; LEF1; ZNF532; RERE; PEG3; JARID2; SALL1; MAF; VEZF1; HOXA5; ZBTB18; RBBP8; LMCD1; ZSCAN18; MEOX2; KDM5D