Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID19145	Mk-1775	GSE70138	NPC.TAK	Human	24h	10uM	EID0095

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	CBFA2T3; GATA3; CREB3; NFE2L2; NFKB2; ZNF688; CDIP1; VDR; TRPS1; TBX1; SRCAP; TBR1; ST18; PRDM12; WNT4; IRF8; TP73; MYBL1; ACTL6B; CAMTA2; EMX1; HOXD1; ZNF467; TULP3; ZNF835; SP100; TCF21; ELF4; FEZF2; BNC1; SP110; ZNF264; TFAP2A; TLX3; DAXX; ARNT2; VGLL1; CRYM; SIRT7; CCNH; MED15; RARG; TGFB1; HIC2; ZNF512B; INSM1; TRIM22; MBD2; IL16; WWC1; HOXB2; PTRF; SOX18; PCGF1; LYL1; CDK9; ZEB1; EPAS1; OSR2; SKIL; SP140L; TWIST1; BACH2; DLX5; CAPN15; ERBB4; RXRA; EN1; STAT4; YBX3; ESR1; KAT2B; CNOT3; JAK2; PEG3; ID1; BCL11A; TRIB3; FOXF2; ZNF83; AEBP1; ID3; HOXD3; TBX3; MYRF; IFI16; ZNF331; PAX5; ZFP36L1; ZFP36L2; ZBED2; PRRX1; TGFB1I1; IRF6; TP63; PAWR; LIN28A; MEIS2; NFATC4; FOSB; ZFPM2; ZNF423; GATA2; NKX3-1; SNAI2; TOB1; KLF6; POU2AF1; MAFB; AHR; CEBPD; FOS
Down-regulation	96	PUF60; HMGA2; ATF1; BCLAF1; ELF2; ETV1; BRCA1; HDAC2; SMARCC1; RBBP4; LPIN2; EED; MAGED1; ECD; ING3; ZMYND11; RHOA; RBM39; FOXO3; TRIM32; NCOR1; NPAT; PBRM1; SFPQ; CCNA2; CRY1; TSC22D4; SSRP1; RNF141; ADNP; NAB1; BMI1; AFF1; TAF7; CTR9; HSF2; ZNF443; ZNF22; ZBTB1; CBX5; TBL1XR1; BRD8; RCOR1; HDAC1; PRKDC; HMGB1; REST; TRRAP; TAF1D; ZNF24; CHD7; MED13; JARID2; HMGB3; DDX5; TSC22D2; NR1D2; FOXJ3; ZNF432; DNMT3B; MAX; TCF12; TAF9B; CTNNB1; HLTF; ENO1; CHD1; PPARGC1A; EDF1; NRIP1; ZMYND8; ID4; MYB; CHD9; CITED1; NCOA1; NPM1; IRX5; ZNF721; TCFL5; SIAH2; KDM5D; SMAD6; VEZF1; ZEB2; PIR; PBX1; MSX1; BHLHE41; ASCL1; ZBTB20; TOX3; ZBTB18; TXNIP; HOXC6; HES1