Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID19109	Belinostat	GSE70138	NPC.TAK	Human	24h	10uM	EID0094

Response Information :

Types	Number	Response transcription factors
Up-regulation	163	EGR1; FOXO4; MYCBP; NR1H2; STAT1; PPARD; STAT3; WWC1; NFYA; RNF141; RUVBL2; DRAP1; NRBF2; CDK9; SETD3; CCNH; PSMD9; MED20; ATF6; TBP; ATF3; IRX5; FOSB; MED7; RUVBL1; SOX2; NFIL3; ERCC2; NR4A2; ETS2; MLXIP; TOB1; ZNF557; TRAF6; CBX6; ZBTB24; ZNF473; HMG20B; CITED2; ZNF131; OVOL2; VDR; ZNF281; JUND; TLE2; RNF14; ZNF324; SNAPC4; SIX5; PITX1; SIRT7; EGR4; IRF7; TLX3; ABT1; PCGF1; ZNF394; NR4A1; NOC2L; CRK; ZBTB43; KLF2; C1D; PTRF; HSF1; CAMTA2; KLF6; JUN; HLX; ZNF165; SREBF1; ETS1; TCEB2; SNIP1; IFNB1; MXD1; TCF21; ZKSCAN1; DBP; COPS5; EDF1; SSX1; TSG101; SMARCD3; ING2; YBX2; EGR3; CCNE1; TCF15; BARX1; CDK7; EGR2; TAF1C; KLF11; HTATIP2; FOSL2; ARNTL; SAFB2; NR3C2; MITF; ELF3; ZNF552; PPP1R13L; IL16; GRHL2; FOXC1; PURA; HOXD1; TFDP2; ZNF239; TCF20; MBD2; RUNX1; SATB2; CEBPG; NR1H4; TGFB1; ELF5; ZNF7; CTR9; ATF5; TRPS1; BRD4; MDM2; TULP4; NR1D2; OSR2; NFE2L3; MXI1; JUNB; NFATC1; TCFL5; VGLL1; CREB3L1; NR4A3; TFAP2A; FOXE1; DDIT3; TFCP2L1; ZNF331; HMGN3; NCOA3; CREM; NKX2-1; PPARGC1A; MED21; SNAI2; KLF4; SIX1; ARNTL2; ZSCAN18; NPAS2; INSR; HOXC10; ADRB2; BCL11B; HHEX; ERG; CALR; KLF5; MYBL1; EMX2; FOS
Down-regulation	219	HMGA2; PCBD1; VPS72; APEX1; SOX11; ZEB1; XBP1; TCF12; BACH1; USP22; SMARCA4; TP53; CHD9; POU5F1B; ZNF532; TLE4; TGFB1I1; SALL1; SPDEF; ZMIZ1; TLE1; FOXM1; ELF2; ARID4B; ZNF32; TBL1X; EZH2; HIRA; CBX5; ADNP; BCLAF1; KAT2B; VGLL4; NONO; DEK; BAZ1A; PATZ1; PHF2; EYA1; USP21; CNOT2; CCNA2; GTF2I; ZFP36L2; ZFX; WDR77; MYCN; UBE3A; CARHSP1; LOXL2; CTBP1; PCGF2; HDGF; ZKSCAN7; ZNF292; IRF5; TCF7L2; BMI1; LIN28A; NRIP1; KDM5B; BATF; TRIM24; MEIS1; RBM39; ZIC3; TSC22D3; ZNF160; TGIF2; ECD; FOXF1; RFX7; BTF3; ABL1; HOXA4; SOX17; HNRNPD; TCF7; ETV4; ZNF432; CENPF; SCMH1; C1QBP; SALL2; MBD4; ZFP30; ZMYM2; FOXJ3; RNF138; CBFB; BIRC2; HEY1; BRIP1; PMS1; ZNF232; DDX17; ERF; ZNF219; ZNF146; HDAC2; RBBP7; ZNF282; PMF1; SMAD4; ETV1; ARID1A; NPM1; BCOR; HOXC4; TAF9B; HOXA5; BASP1; ZNF124; HIC2; ZNF516; NR2F1; ZNF227; ZIC1; PQBP1; BRD3; ZFP64; ASXL1; SETD2; KAT8; NFKBIA; THAP10; OLIG2; PROX1; HOXB6; ZBTB1; ZNF721; ZNF512B; SSBP3; NR0B1; SAP30; NR2F2; ZNF611; SMARCC2; MNDA; RBBP4; GLI3; ZNF410; CUX2; IFI16; LEF1; TBX3; RAN; PSPC1; ZNF652; PBX1; ATF4; CTNNB1; VEZF1; NCOA2; YEATS4; IKBKAP; ERBB2; FUBP1; TAF1D; PDLIM1; ETV5; GTF3A; ZNF24; YAP1; ZMYND8; E2F5; TCF4; MED14; HDAC9; TRIM29; RERE; MAGED1; KDM5D; ARID5B; GLI2; HMG20A; DMTF1; ESRRG; ID3; RXRA; MEIS2; ZHX2; SSBP2; ZFP36L1; HMBOX1; LITAF; ING3; SMAD6; ZNF423; SFPQ; HMGB2; FOXF2; NFKB1; HMGB1; RBPJ; HLF; TEAD4; KAT6B; FLNA; TBL1XR1; PTTG1; TOX3; FOXD1; WHSC1; ZEB2; ZNF217; TXNIP; SUV39H1; BCL6; BCL11A; HES1; MTA1; ID4; MSX1; DACH1; PBX3; SMAD3; MECOM; NFATC3