Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID19091 Gsk-1059615 GSE70138 NPC.TAK Human 24h 10uM EID0094
Types Number Response transcription factors
Up-regulation 167 FOXO4; HDAC9; PRPF6; CRTC1; ZNF224; ZMIZ2; ZNF667; CALCOCO1; HOXC4; SSX3; TCEA2; POU2AF1; JUN; ZNF219; TCF15; KDM4C; ZNF692; HSF4; KAT2B; MZF1; SSX1; TBX19; ZFP2; NCOA2; CXXC1; TCF20; EZH1; VDR; HDAC5; HMX1; ING4; FOXO3; CDX2; PRMT2; MYOG; COPS5; FOXG1; FOXA2; GTF2F1; CIC; MBD4; ZNF506; ZNF227; ZNF384; BTF3; HDAC7; CDK9; PRDM14; SAFB; NKX2-1; ATN1; PPP1R13L; DDX17; ZNF665; CREBL2; CIITA; NHLH1; YBX1; EVX1; GTF2I; THRA; TAF1; BRD8; MYCL; FOXJ1; SMARCC2; SPIB; TAF1C; ELF3; TFCP2; SP140; TP63; PROP1; TCF25; CHD4; ARID4B; SOX9; ZNF266; ATF4; EPAS1; HOXC8; TSC22D1; EYA1; SIX6; HR; MNX1; BARX2; SOX21; SP2; SATB1; ZNF83; SSBP3; PHOX2B; HOXC11; ATOH1; BCOR; TOPORS; EYA2; RARG; MED15; TFEB; PHIP; ZNF551; KLF15; ZNF419; NONO; BRWD1; BCL11A; ZFHX3; POLR2A; MED14; HIVEP2; PAX5; IRF4; TERF1; MDM4; BBX; PAXBP1; ZNF211; MXI1; ZNF580; TCEA1; TCF7; ETV5; MYCN; INSM1; ZNF160; NR5A2; GATA1; ZNF264; PCGF3; BRD2; ASCL1; ZNF544; JUP; HMGA1; NR1D2; FUBP1; KLF9; BACH2; TOB1; BHLHE41; BAZ2B; NFE2L3; NFATC3; DLX5; FOXF2; TXNIP; PAWR; NR4A2; SATB2; ZBTB18; HMG20B; FLNA; TOX3; HLF; CALR; ZBTB20; MYBL1; BTG1; HOXD1; LEF1; ZHX2; ARNT2; HOXC6; ID1; PSIP1
Down-regulation 40 ATF6; XBP1; GTF2A2; RUVBL1; CCNA2; MYC; TFDP1; PREB; RNF14; MYCBP; CCNE1; ESRRG; RBBP8; YAP1; CUX1; TFDP2; HLX; SUB1; TRIP6; FOSL2; TBL1X; AR; C1QBP; FOXN3; GATAD2A; GTF3A; CREB3L2; BASP1; SMAD6; SMARCD3; MAGED1; TEAD4; DNMT3B; FOXO1; NFE2; MTDH; MSX1; SIAH2; WT1; HEY1