Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18799	Vorinostat	GSE70138	NPC.TAK	Human	24h	10uM	EID0059

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	CREG1; STAT1; ETS1; NR4A1; PPARD; GTF2A2; FOSB; CRK; DRAP1; FOXO4; ATF3; MEF2C; MNAT1; CCNH; CEBPB; JUN; MYCBP; TFAP2C; EGR3; NFKB2; ZNF324; FOS; NFIL3; CBX7; ZBTB7A; EGR2; BRF2; HMG20B; PREB; HDAC1; DLX4; TAF4B; EGR1; IRF3; SP100; NOC2L; TOB1; RBBP5; GTF2F1; SND1; RNF6; TGFB1; SPIB; CBFA2T3; NRBF2; SUPT4H1; JUNB; PPP1R13L; TDP2; DDIT3; CREM; RUNX3; C1D; NFE2L2; NR4A2; EPAS1; STAT3; NR4A3; NR3C2; ZNF224; SAP18; KLF2; SATB2; ZNF331; TERF1; ASH2L; IRF7; MYBL1; CRYM; MDM2; BCL10; SP110; CTR9; SUB1; JUND; TLE2; FOXA2; TFAP2A; SPDEF; ANKRD1; ZNF593; KLF5; MXD1; NR0B2; SNAI2; VDR; COPS5; ETV5; ELF5; SOX10; CBX6; TSG101; HTATIP2; KLF6; HBP1; LMCD1; SMARCA2; PAX5; ZNF394; SIX1; CD3D; CREBL2; TRIB3; ELF3; BRD4; PBXIP1; TCF7; HOXD1; POU2AF1; SMAD7; BBX; TSC22D1; SMARCD3; STAT4; MITF; CITED2; ADRB2; CALR; MED21; ARNT2; TRPS1; KLF4; HHEX; PITX1; OSR2; LITAF; MBD2; NFE2L3; NR1H2; PSIP1
Down-regulation	192	HMGA2; EZH2; PCBD1; SMARCA4; SOX11; NUP62; TP53; TSC22D3; CCNA2; PATZ1; TCERG1; TCF4; GABPB1; PHF2; XBP1; HDAC2; ETV1; PUF60; ZBED1; HDGF; ARID4B; ARL2BP; CREB1; SMARCC1; MYCN; MTA1; ERBB2; ZNF532; BRD3; NFKBIA; TRAK1; CHD9; KAT6B; BCLAF1; WIZ; SPEN; WHSC1; SUV39H1; CTCF; ZKSCAN7; NRIP1; HNRNPD; PMF1; VPS72; CBX5; HMGB3; MAGED1; RBM14; ZNF146; SCMH1; SMARCE1; ARID1A; TFEC; ADNP; ZNF189; ZNF84; HES1; MEIS1; ZNF107; RBM39; ZNF282; HOXB2; MED12; CNBP; ZMYND11; FOXM1; SFMBT1; TCF12; BAZ1A; RFX7; SOX2; BRIP1; SETDB1; ZEB1; ZBTB1; PKNOX1; ZNF43; HMGB2; ZFP64; ZNF22; BAZ2B; MED17; TOX3; BRD8; KMT2A; PBRM1; CENPF; APEX1; ZNF629; NFKB1; PCGF2; ZFPM2; PMS1; BATF; PLAGL2; SALL1; MLLT10; ATF7IP; HMGB1; MGA; VEZF1; TLE4; ZNF711; KLF7; NCOA6; NHLH2; DEK; ZNF93; DDX5; NCOA4; HIVEP1; ZNF423; TAF9B; ID4; ASXL1; ZSCAN31; FUBP1; GLI2; TGIF1; ZNF292; CARHSP1; ZNF248; ZNF551; SP3; E2F3; ID3; RNF138; CHD3; ZNF302; HOXB6; DAXX; ZNF32; ZIC1; ZNF529; ILF2; CREBZF; MED24; SCAND1; ZEB2; PBX3; NFE2L1; SALL2; TBL1X; ZNF117; TAF1D; SMAD1; CTBP1; SETD2; ZNF83; ZHX2; SMAD3; HIC2; EMX2; DDX17; TRRAP; NKX2-2; BCOR; ING3; ZFP36L2; SAP30; PITX2; AFF1; SLC2A4RG; TBL1XR1; ZNF24; DACH1; MYCL; BMI1; MYB; BASP1; FOXD1; HOXB5; YBX1; PHOX2B; SOX17; DLX2; HOXB7; ATF5; PLAGL1; PDLIM1; BCL11A; CHD7; FLNA; ATF4; FOXF1; HOXC6; PBX1; DNMT3B; LEF1; KDM5D; NFATC3; TLE1