Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18794 Nvp-bgj398 GSE70138 NPC.TAK Human 24h 10uM EID0059
Types Number Response transcription factors
Up-regulation 71 TCEB2; PPARG; NCOA2; ZBTB7A; TSHZ2; APEX1; HBP1; ID1; ZNF423; TRIB3; UBE2B; MED14; OSR2; SRCAP; TFAP2A; ZNF3; MEOX2; HOXA10; GTF3A; HOXD1; PQBP1; HIRA; MECOM; INSM1; COPS2; OVOL2; TCEA1; RNF6; BACH2; JUP; RBPJ; KLF11; PFDN5; KLF5; TCF7L2; ID3; SAP18; FOXF2; CRYM; GATA6; HOXB7; ELF3; IRF1; WWC1; ATF4; TP63; EYA1; SNAI2; FOXO1; ESR1; MEIS2; CEBPZ; AEBP1; PAWR; ZNF217; TFAP2C; ARNT2; BTG1; ST18; INSR; POU4F1; MYRF; BCL11A; ZFPM2; DLX5; VDR; MXI1; NFATC3; BASP1; TLE1; PSIP1
Down-regulation 43 HMGA2; ETV1; EZH2; CCNA2; HES1; ZNF274; LZTS1; BRCA1; ZMYND11; TAF9B; BLM; CENPF; MED1; ZSCAN18; ZNF189; SLC2A4RG; MAGED1; HOXC10; ING3; PBX3; FOXM1; HMGB3; ZNF43; CREB3L2; FOSB; TRPS1; SALL1; WWTR1; HMGB2; ENO1; PURA; ZBTB38; CALR; PTTG1; ZEB2; TSC22D1; FOXC1; DNMT3B; ZIC1; BHLHE41; MAFB; RBPMS; GATA3