Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18742 Wz-4002 GSE70138 NPC.TAK Human 24h 10uM EID0059
Types Number Response transcription factors
Up-regulation 341 NFKB2; SUPT6H; ZNF350; MEF2C; NFATC4; TAF1C; FEZF2; ARHGAP35; TRIP11; ZNF195; FOXO4; PPARA; MKL1; TRIM33; PRDM14; PDX1; FOXC2; CSDE1; BRD2; HOXB1; SPI1; ERBB4; RSF1; ZNF362; SRCAP; TFAP2A; TP63; KLF13; NKRF; ZNF580; SP110; RFX1; THRB; EMX1; CREB3; CNOT3; MAML3; RORC; PPP1R13L; ZNF816; FOXH1; CAMTA2; VENTX; NR1H4; HIPK2; ZNF814; CSDC2; CEBPB; ZBTB7B; E2F4; ALX3; EPAS1; ZIC3; RXRG; SP100; TULP2; ZNF239; CIITA; CBX7; ZNF613; ZNF787; TBR1; ATF7; MTF1; TAF4B; CCNH; CBX4; UTF1; ASCL3; ZNF835; HNF4A; TEF; HSF4; ZNF154; EYA3; MED14; LDB1; ZNF34; CALCOCO1; TFEC; WHSC1L1; ETV3; DYRK1B; NFX1; ZNF33B; ZNF175; HSF1; NR5A1; ONECUT1; ZHX2; NFE2; ZNF552; ZNF391; BRD4; HDAC5; TP73; PRDM12; ANKRD1; ZNF671; JUP; LHX6; ZNF235; ZBTB3; ESR1; IRF6; PCGF1; ZNF528; ZNF407; PAX4; CNBP; ZNF75D; ZNF124; ZNF780B; ZNF682; ZNF304; NR0B2; ZNF132; GCM2; POU1F1; ZBTB7A; CHD2; MNX1; SOX21; ARNT2; FOXE3; ZNF471; TFEB; ZNF331; PROP1; PNRC1; TSHZ2; FOXO3; HIC1; REL; CREG1; SETDB1; PRDM9; TGFB1; BNC1; PKNOX2; SCRT1; TDP2; POU6F2; BRF2; MEF2D; FOXF2; ZNF507; ZSCAN2; ARNTL; HNF4G; ZNF667; LIN28A; POU2F3; SSX7; ZNF214; STAT2; TRIM22; TRIB3; CDX1; ZNF674; ID2; KDM4C; BNC2; ZNF467; RARG; CEBPZ; NR2E1; HLX; ZSCAN9; ZBTB44; LYL1; PQBP1; MYBL1; PRDM2; ZNF80; NFKBIA; ZNF157; NFIX; ZNF444; FOXB1; PRDM10; MZF1; ZNF215; BRDT; KAT6B; BARX1; SCAI; DOT1L; ZNF81; HIVEP1; TAF6L; TRIM29; CALR; HOXD1; ASH1L; SUPT4H1; CRYM; MYNN; TOB1; ZXDC; HOXC5; THRA; LZTR1; ESRRA; IRF8; RING1; KLF11; CRTC1; THAP7; IRF5; SOHLH2; OVOL2; ID1; TBX1; SP1; MDFI; SIRT7; ATN1; ZNF415; MXI1; CEBPD; ATOH1; ZNF544; SOX3; NKX2-1; ZBED2; ZSCAN16; MNDA; ERG; SNAI2; ZNF695; STAT6; KLF1; MAK; TFCP2L1; MYCL; CARF; NEUROD1; SKIL; LHX3; ZNF354A; SOX18; ZFP36L1; CDIP1; DDIT3; ZNF83; ZBTB43; HDAC9; KLF7; RXRA; HHEX; POLR3C; FOXG1; ATF5; IRF7; JUN; BCL6; ZNF281; ZFHX3; PITX1; POU2AF1; NCOA2; KLF3; SP140L; NANOG; ZFPM2; EN1; PBX2; ZNF589; SPDEF; ZNF573; ARID5B; ZNF593; VDR; IRF9; GFI1B; VGLL1; GATA1; HBP1; EP300; ZNF117; TFDP2; TCF21; NR3C1; PBXIP1; HLF; PAWR; JAK2; MED15; MECOM; SMARCA2; ZNF654; BTG1; ZNF394; HMGA1; CBX6; WWC1; BCL3; FLI1; NR1H2; ZNF165; SPIB; TXNIP; ZSCAN31; TCF7L2; CREBL2; MAFB; SOX17; KLF4; ST18; SOX13; BCL11A; IRX4; NR4A2; TCEA1; ZNF423; MXD1; HOXB5; INSR; PHOX2B; TRPS1; BHLHE41; TAL1; ATF3; FOXA2; TOPORS; DACH1; PAX5; SMAD7; AHR; FOS; JUNB; KLF5; ID3; FOSB; MBD2; RUNX3; NFATC3; YBX3; EHF; ASCL1
Down-regulation 142 HMGA2; EZH2; RUVBL1; CCNA2; HES1; HDAC2; ETV1; RHOA; SUV39H1; GTF2A2; RBBP4; HNRNPD; BRCA1; PARP1; ERCC3; SMARCC1; SOX11; PUF60; TRRAP; MAGED1; WHSC1; SMARCE1; HMGB2; BLM; CARHSP1; EWSR1; CRY1; ARNTL2; BMI1; NUP62; HSF2; RBM14; SMARCA5; BRD3; NR2F2; CENPF; ECD; BATF3; ZNF189; E2F6; TAF9B; ITGB3BP; YWHAB; AEBP1; YAF2; CBX3; BCLAF1; MED27; ZMYND11; LOXL2; NELFB; TCF12; RBBP7; PSMC3IP; NFYB; PIAS3; SIAH2; CBFB; VEZF1; PHF2; NCOA6; FOXJ3; MTF2; ZNF721; ZNF160; PCGF2; ZNF267; PRKDC; DNAJC1; MSX1; IKBKAP; ATF7IP; ZNF443; TULP4; NEDD8; NCOR1; HDAC1; HLTF; C1QBP; PMS1; CHD9; TRIM32; MLXIP; DDX5; HOXA10; CHD7; ETS1; TGFB1I1; HMGN3; FUBP1; ID4; MKL2; MYCBP; EGR2; NRIP1; NKX2-2; SFMBT1; HMGB3; RNF4; NCOA1; HOXA11; KMT2A; TCF4; REST; IRX5; TLE4; SUB1; HSBP1; CHD1; TAF1D; CTNNB1; YBX1; APEX1; ZNF652; SFPQ; PTTG1; MYCN; NR0B1; NAB1; SP3; ELK3; NR2F1; MED21; DNMT3B; XRCC6; RAN; ETS2; LEF1; HOXB7; GFI1; BCL11B; WWTR1; RBPMS; TOX3; ENO1; BAZ1A; ZMYND8; ZEB2; HOXC6; HEY1; BASP1; PSIP1