Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18734 Gsk-1059615 GSE70138 NPC.TAK Human 24h 0.12uM EID0059
Types Number Response transcription factors
Up-regulation 56 ZNF117; BRCA2; TMF1; ZBTB18; CCNE1; SIAH2; ZNF266; TBX21; KAT2B; CD3D; HOXA1; TCF7L1; VGLL1; ZNF350; IRX4; ARID5B; JARID2; IRX5; YEATS4; PQBP1; ZNF217; ZNF529; TGIF1; RUNX1; NEUROD1; CRYM; NFAT5; ERBB4; STAT4; HMGB3; IRF4; BCL11B; NKX2-1; IRF7; INSM1; GATA3; ELF5; CCNC; LIN28A; AFF1; WT1; MYCN; MAGED1; FOXA1; ASCL1; EGR3; ZNF423; POU2AF1; FLNA; AEBP1; ESR1; LEF1; NFATC3; YBX3; MAFB; PEG3
Down-regulation 51 MTA1; CRK; CSDE1; TRIM16; TRIP4; LITAF; PTRF; MNT; MYCBP; RBBP5; ZKSCAN1; E2F5; MECOM; PIR; SP140L; C1QBP; KLF4; CREB3L1; HDAC1; IKBKAP; GATA6; KLF9; TRIM28; ZNF430; ZNF394; PBX1; MBD2; HOXB7; NR3C2; JUNB; SOX10; YWHAB; EGR2; SMARCA2; CTR9; ZNF160; NR4A1; MEIS2; NR2F2; SPIB; ID1; KDM5D; TOX3; FOXF1; SNAI2; PBX3; BHLHE41; KLF6; SMAD1; BASP1; PSIP1