Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18710	Ibrutinib	GSE70138	NPC.TAK	Human	24h	0.12uM	EID0059

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	TFDP1; RBBP5; ZNF107; ZNF200; ABL1; ZNF177; TERF2; NFE2; HDGF; ARNTL; MNAT1; PRDM10; SCAI; ZKSCAN1; RBM39; HDAC4; ZBED1; L3MBTL1; TRIB3; ING1; MDM2; SIM2; CIR1; MED7; MTF2; BTG1; TFCP2; CCNH; RNF141; GATA4; ZNF573; FOXL2; WWP1; TWIST1; POU4F1; TGIF1; ZNF117; PSMC3; ZNF423; INSR; CEBPB; ZNF23; MYBL1; TFDP2; TCF7; CTR9; TAF1A; ZNF7; MED23; MED6; ZNF516; ZNF248; ZNF623; YEATS4; HOXC4; TXNIP; MYB; KLF5; CRYM; TBL1XR1; SATB2; CNOT6; HOXC6; LEF1; PNRC1; ESR1; ZNF264; ZBTB18; CREB3L1; ELF3; PRRX1; LPIN2; NKX2-1; OSR2; HMGB1; ZFP36L2; TCF4; SOX9; PITX2; NR0B1; VDR; KLF10; MXI1; TRIM22; NR3C2; AEBP1; PAX5; FOXO1; ERG; MSX1; NFATC3; TBX3
Down-regulation	62	BRPF1; PCBD1; GABPB1; SUPT5H; TADA3; CCNE1; ELF4; TGFB1I1; UBP1; ARID5A; COPS2; MEF2A; PBX1; ZBED4; PCGF2; KLF9; IL16; TGFB1; CHD3; CAPN15; FOSL2; CBX6; ZFHX3; ZIC1; TEAD3; MAFF; NEUROD1; TSC22D2; BNC2; PHF1; SLC2A4RG; CREM; ZNF93; HOXB2; NR4A3; ZNF512B; HEY1; RBPMS; BAZ2B; SOX11; HOXB7; TFAP2A; INSM1; EGR2; HDAC9; ZEB1; TLE2; SMAD7; PIR; TRIP6; JUNB; PDLIM1; SMARCD3; PAX6; MEIS2; RUNX3; ZBTB38; ZSCAN18; ZFP36L1; ELK3; PSIP1; NR2F1