Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18584 Gsk-1059615 GSE70138 NPC.TAK Human 24h 0.04uM EID0058
Types Number Response transcription factors
Up-regulation 37 PRDM2; THRA; EGR1; TCF7L2; ZNF107; INSR; TAF4; ZNF506; ZNF629; DEAF1; SMAD3; ERBB4; BRD8; TRIM24; MED20; HDAC5; WWC1; PHF20; TBL1X; ELF3; ZBTB18; E2F2; MED24; ZNF117; MYB; ZNF264; KDM5D; ZNF217; EYA2; CUX1; DLX5; ESR1; RBPMS; HMGN3; LEF1; ID1; EGR3
Down-regulation 21 CRY1; IRF9; PIR; RUNX3; NFKB1; IFI16; CREM; CUX2; BCL11B; MED1; CEBPB; TRIM22; BASP1; INSM1; ZIC1; PEG3; MECOM; SNAI2; BHLHE41; NFATC3; RELB