Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18557 Ibrutinib GSE70138 NPC.TAK Human 24h 1.11uM EID0058
Types Number Response transcription factors
Up-regulation 32 NR3C1; TFAP2C; TLE2; ZFPM2; CD3D; TFAP2A; ERG; NAB1; HLTF; ZNF512B; INSR; ZMYND8; BASP1; NR4A2; MXI1; IRX5; TRIM16; RUNX3; TGFB1; TBL1X; NCOR2; TRIM29; NR2F1; MYB; ZBTB18; ESR1; FOXF1; BHLHE41; ZIC1; POU2AF1; EGR3; PSIP1
Down-regulation 24 CREB1; HMBOX1; SIX2; BACH1; ATF7IP; LMCD1; RBPJ; MED21; ZSCAN18; RNF138; E2F5; KLF6; EYA1; DDIT3; ZNF91; TWIST1; MEIS2; SALL1; SOX9; ID4; ZFP36L1; TXNIP; MECOM; NFATC3