Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18445	Withaferin-a	GSE70138	MCF10A	Human	3h	10uM	EID0024

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	EGR1; JUN; STAT1; NRF1; UBE2B; POU4F1; PHIP; HMGB2; SUV39H1; AFF4; XBP1; CCDC59; ATF4; ZNF528; TAF9; NCOA1; CREM; DDIT3; HOXA1; ATF3; MAFB; NCOA2; NR4A3; NR4A1; GATA4; ZMIZ1; POLR2A; ZNF516; SATB2; HSBP1; AATF; OSR2; POU2AF1; FOXA2; HAND1; JAK2; PITX2; TBL1X; SSX1; IRF1; TGIF1; TRRAP; ZNF200; EGR3; NR1H3; PTRF; NFATC1; BATF3; MSX1; BRD8; RLF; SOX9; CEBPG; NRBF2; FOXL2; BCLAF1; TLE4; NR4A2; ISL1; CTR9; BATF; BLM; LEF1; PPARGC1A; FOSL2; ARNTL; KLF4; HLF; JARID2; HLTF; ZNF331; HOXB7; AEBP1; TOB1; TFEC; ZEB2; NKX3-1; EGR2; BTG1; TSC22D2; BRD2; ZBTB38; ZSCAN18; PEG3; FLI1; GATA6; PBX3; PAX5
Down-regulation	56	MYC; NFKBIA; SIM2; FOXA1; CTBP1; HES1; HOXB2; ID1; MEOX1; HDAC9; ASH2L; ETV4; NR2F6; MYBL1; TFDP2; APEX1; ZNF12; TWIST1; GTF2I; HOXB13; ZFHX3; ZNF623; SHOX2; KLF13; MAZ; PCGF2; CEBPA; TEAD3; GRHL2; ASCL1; SPDEF; LITAF; NFIB; WT1; TRIM22; NR2F1; HOXB5; CUX2; THAP10; PFDN5; SALL2; AHR; ADRB2; NR2F2; TFAP2C; TRIM29; IFI16; TRPS1; TGFB1; ST18; CRYM; DACH1; ARNT2; BASP1; E2F2; IKZF1