Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID18444 Mitoxantrone GSE70138 MCF10A Human 3h 0.04uM EID0024
Types Number Response transcription factors
Up-regulation 82 MZF1; REPIN1; ZNF787; ZMYM2; MEIS2; ZNF586; ZNF551; CNOT3; ZSCAN9; ZNF329; EHF; RAD21; GTF2IRD1; KAT2B; ZNF211; ZNF264; FOXJ1; ZNF134; ZNF671; HOXD3; ZNF606; ZNF652; AEBP1; HOXD1; ZNF580; PLAGL1; ZNF587; ZNF423; JUP; ZNF44; ATN1; SOX13; SMARCB1; TRIM24; SCAND1; GLI2; MYCL; ZNF217; ZNF350; TCEA1; TCF21; LEF1; EYA1; ZNF91; TEAD3; ZNF43; TGFB1I1; ZNF467; AES; SMAD7; WT1; TCEA2; ZNF544; CHD7; BCL3; POU2AF1; ID3; TRIM29; TCF4; CTNNB1; ZFPM2; BHLHE40; ETS2; HOXB6; PAX5; IFI16; ZEB1; ZSCAN18; FOXF1; SOX17; ST18; MECOM; EMX2; TOB1; ID1; ATF3; ARNT2; PIR; HOXB2; TFAP2C; BCL11A; VPS72
Down-regulation 37 HOXA5; BRD3; TAF9; ZNF189; SOX4; EDF1; FOXC1; SOX9; ZBTB43; MAGED1; ETS1; IRX5; SPEN; BAZ1A; NR1H3; HOXC10; RUNX1; NFIB; JARID2; ELF1; RXRA; KLF4; MAFB; PURA; ZBTB38; ADRB2; SMARCA2; HOXC6; SAP30; CENPF; NR2F2; FLNA; EGR3; WWTR1; TFEC; EGR2; MEF2C