Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID18439	Mitoxantrone	GSE70138	MCF10A	Human	3h	10uM	EID0024

Response Information :

Types	Number	Response transcription factors
Up-regulation	50	PHOX2A; HDAC1; HAND1; ZMYM2; SMAD6; AEBP1; PAWR; SNAI1; FOXJ1; RXRA; GATA3; ZNF552; GRHL2; PIR; PPP1R13L; IRF5; HOXC4; MYB; PRRX2; TBX2; CIZ1; HTATIP2; ACTL6A; CTBP2; CREB3L1; MECOM; MLXIP; PRRX1; CSDE1; STAT1; RNF141; WT1; LMCD1; NFATC3; KAT2B; TCF21; IRF7; RBBP8; SSX1; TXNIP; MYCL; ZSCAN18; FOS; ZBTB18; HOXC6; CREB1; SATB1; BHLHE41; MYRF; GATA6
Down-regulation	160	MYC; NFKBIA; FOSL1; ADRB2; ARID4B; CEBPD; CEBPB; NRIP1; FOXO3; HOXA10; LITAF; MTF2; CHD1; HMGA2; RNF4; ZBED1; HES1; TAF1D; TRIM27; HOXA5; ZNF184; CREB5; SNIP1; ZNF281; BHLHE40; ZNF573; ZNF189; ZNF232; DDX17; ZNF574; ZNF529; ZNF571; SOX11; BAZ1A; ZNF263; CAMTA1; DDIT3; BANP; KAT6A; BACH2; APEX1; NR1H3; HMGA1; MED17; ZNF131; CHD9; ZNF12; RLF; ZNF394; SIAH2; UBE2I; HLF; PIAS1; HHEX; TFAP2A; PATZ1; ZNF652; EGR4; HMBOX1; BTG1; PNRC1; MAFG; ZNF107; ZNF14; NFIB; TERF2; NKX3-1; NKX2-2; FOXJ3; ZNF345; PRDM10; PA2G4; SMARCA1; PLAGL2; REL; RNF111; ZBTB16; ELF1; NFIL3; ZNF536; ERF; PLAGL1; ABL1; TGIF1; MYBL1; BCL10; ID1; SHOX2; SPIB; DNMT3B; HOXA1; KMT2A; NFKB1; NR2F1; ZNF93; BCL6; HNRNPD; MYT1L; PAX6; SMAD7; ZNF43; OSR2; VEZF1; STAT6; ZNF91; ZFP36L1; MKL2; ZNF267; HMGB3; JUND; ZNF623; ZIC1; PEG3; YBX1; ELF5; MAFF; ZNF264; ZNF117; AHR; RUNX3; SALL1; EGR2; STAT4; SMAD1; SOX10; TCF7L2; ZNF721; ZNF430; HIRA; KLF9; LOXL2; HOXB2; CITED1; FOXF2; ZBTB20; ZFP36L2; BRD2; EGR1; HEY1; MAF; MEIS2; ZNF512B; TLE1; HIC2; EGR3; SOX9; PAX5; TOX3; TSC22D2; ZEB2; WWTR1; ZEB1; ELK3; TRPS1; ARID5B; SUV39H1; ZNF586; BASP1; E2F2; IKZF1